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- Denitsa Docheva, Sebastian Andreas Mueller, Martin Majewski, Christopher H. Evans
- Advanced drug delivery reviews
- 2015
Tendon injuries are common and present a clinical challenge to orthopedic surgery mainly because these injuries often respond poorly to treatment and require prolonged rehabilitation. Therapeutic… (More)
- Denitsa Docheva, Cvetan Popov, Wolf Mutschler, Matthias Schieker
- Journal of cellular and molecular medicine
- 2007
The identification of mesenchymal stem cells (MSCs) in adult human tissues and the disclosure of their self-renew-al and multi-lineage differentiation capabilities have provided exciting prospects… (More)
- Wolfgang Böcker, Zhanhai Yin, +8 authors Matthias Schieker
- Journal of cellular and molecular medicine
- 2008
Human mesenchymal stem cells (hMSCs) can be readily isolated from bone marrow and differentiate into multiple tissues, making them a promising target for future cell and gene therapy applications.… (More)
- Julia Kohler, Cvetan Popov, +9 authors Denitsa Docheva
- Aging cell
- 2013
Although the link between altered stem cell properties and tissue aging has been recognized, the molecular and cellular processes of tendon aging have not been elucidated. As tendons contain… (More)
- Elias Volkmer, Bobby Cherian Kallukalam, +8 authors Matthias Schieker
- Tissue engineering. Part A
- 2010
Osteogenic differentiation of human mesenchymal stem cells (hMSCs) into osteoblasts is a prerequisite for subsequent bone formation. Numerous studies have explored osteogenic differentiation under… (More)
- Denitsa Docheva, Daniela Padula, Cvetan Popov, Wolf Mutschler, Hauke Clausen-Schaumann, Matthias Schieker
- Journal of cellular and molecular medicine
- 2008
Within the bone lie several different cell types, including osteoblasts (OBs) and mesenchymal stem cells (MSCs). The MSCs are ideal targets for regenerative medicine of bone due to their… (More)
- Florian Haasters, Wolf Christian Prall, +6 authors Matthias Schieker
- Journal of anatomy
- 2009
Human mesenchymal stem cells (hMSC) are a heterogeneous cell population, which is reflected in varying morphological and biological properties. Three subpopulations with intrinsic characteristics can… (More)
- Florian Haasters, Hans Polzer, +6 authors Matthias Schieker
- Knee Surgery, Sports Traumatology, Arthroscopy
- 2011
Bupivacaine, ropivacaine, and morphine are commonly administered intraarticularly after anterior cruciate ligament (ACL) reconstruction. However, their effects on human tendon stem/progenitor cells… (More)
Human mesenchymal stem cells at the single-cell level: simultaneous seven-colour immunofluorescence.
- Matthias Schieker, Christoph Pautke, +7 authors Wolf Mutschler
- Journal of anatomy
- 2007
Extracellular, intracellular or surface proteins can be used as putative markers to characterize human mesenchymal stem cells (hMSC). However, these markers are also expressed by other cell types and… (More)
- Denitsa Docheva, Daniela Padula, +7 authors Matthias Schieker
- European cells & materials
- 2010
Periodontal ligament (PDL) can be obtained from patients undergoing orthodontic treatment. PDL contains progenitor cells that can be expanded and differentiated towards several mesenchymal lineages… (More)