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A novel animal model of insulin resistance, the fructose-fed Syrian golden hamster, was employed to investigate the efficacy and mechanisms of action of rosuvastatin, a HMG-CoA reductase inhibitor, in ameliorating metabolic dyslipidemia in insulin-resistant states. Fructose feeding for a 2-week period induced insulin resistance and a significant increase in(More)
OBJECTIVE To detect movement intention from executed and imaginary palmar grasps in healthy subjects and attempted executions in stroke patients using one EEG channel. Moreover, movement force and speed were also decoded. APPROACH Fifteen healthy subjects performed motor execution and imagination of four types of palmar grasps. In addition, five stroke(More)
OBJECTIVE To compare the extent to which gait speed measured in the clinic setting differs from that measured in the community. DESIGN Participants completed the 10-m walk test at a self-selected speed in a clinic SETTING. Following this they completed a 300-m community-based walking circuit that covered a variety of environmental conditions. Gait(More)
PURPOSE To explore the barriers and facilitators to engagement in physical activity from the perspective of people with multiple sclerosis (MS). METHOD This study adopted a qualitative descriptive design, using semi-structured interviews. Participants were recruited through local MS Societies and one District Health Board as part of a larger study. Ten(More)
OBJECTIVE To explore the test-retest reliability and construct validity of the standardized Physical Activity and Disability Survey (PADS) and its acceptability to people with multiple sclerosis. DESIGN Participants completed the PADS twice with seven days between repeated measures, while also wearing an Actical accelerometer. Semi-structured interview(More)
INTRODUCTION Telehealth is an all-inclusive term for the provision of health services using information and communication technology. Videoconference delivery is one form of telehealth whereby a synchronous, two-way audio and visual connection is made between two or more sites. Videoconference is used in remote areas to improve access to healthcare, perform(More)
The use of DNA amplification fingerprinting (DAF) as a tool for monitoring mixed microbial populations in bioreactors was evaluated. Short (8-mer or 10-mer) oligonucleotides were used to prime DNA extracts from various biological reactors during polymerase chain reaction (PCR) amplification. The reactors examined in this study included two sets of anaerobic(More)
The paper describes a new type of evolving connectionist systems (ECOS) called evolving spatio-temporal data machines based on neuromorphic, brain-like information processing principles (eSTDM). These are multi-modular computer systems designed to deal with large and fast spatio/spectro temporal data using spiking neural networks (SNN) as major processing(More)
OBJECTIVE To assess the feasibility, acceptability, and psychometric properties of Actical accelerometers in people with multiple sclerosis (MS). DESIGN Participants attended 2 testing sessions 7 days apart in which they completed 6 activities ranging in intensity while wearing an Actical accelerometer and Polar heart rate monitor. Perceived exertion was(More)