Denise Strubel

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In the cerebrospinal fluid (CSF) of 53 patients with senile dementia of the Alzheimer type (SDAT) and 12 elderly controls, we measured somatostatin (SLI) and its molecular forms: high-molecular weight form (HMV-SST), somatostatin-14 (SST-14), somatostatin-25/28 (SST-28/25), and des-ala-somatostatin (des-ala-SST) using high pressure liquid chromatography(More)
There is some evidence that Parkinson's disease (PD) seems to be a heterogenous and generalized brain disorder reflecting a degeneration of multiple neuronal networks, including somatostatinergic neurons. Somatostatin-like immunoreactivity (SLI) and its molecular forms, high molecular weight form (HMV-SST), somatostatin-14 (SST-14), somatostatin-25/28(More)
Although osteoporotic fractures of the sacrum seem to be a well-known entity, their associated rate of neurological complications has not been assessed in the literature. The authors report three such cases of nerve root compromise in elderly women and conduct a literature review. Based on their review, they estimate the incidence to be approximately 2%.(More)
Through a national survey, the SFGG's UCC Task Force worked and liaised with the DGOS as to establish a national inventory of the UCCs in France. 43 of the 55 newly opened UCCs in 2011 filled up the survey. These UCCs largely supported patients meeting the admission criteria's from the book of specifications edited by the public department. Those patients(More)
Wandering is a frequent behavior disorder in demented patients. However, it remains ill defined and insufficiently studied. It is characterized by repeated, prolonged and sometimes compulsive need to walk, with or without aim. Its frequency increases with the severity of dementia among institutionalized subjects and Alzheimer's disease patients. It may(More)
The end of life among patients affected by dementia may occur at any stage of the disease. It has an influence on care, nursing team and family. Death usually results from associated pathologies, mainly cardio-vascular and infectious diseases. Pain must be carefully searched for because its expression is altered by dementia. The measurement of pain is based(More)
The concentration of substance-P-like immunoreactivity (SPLI) and somatostatin-like immunoreactivity (SLI) in the lumbar spinal fluid of senile parkinsonian patients (mean age 77.6 +/- 6.7 years) and senile control patients (mean age 83.5 +/- 5.6 years) were determined by specific radioimmunoassays. Mean SPLI and SLI levels in the control group were 8.1 +/-(More)
Eighteen women with senile dementia of the Alzheimer type were observed in two situations of mirror-image stimulation, which were repeated after a 3-week interval. Six out of six subjects scoring 5 on the Global Deterioration Scale of Reisberg et al. reacted appropriately to an unfamiliar mark on their forehead when they observed it in the mirror, thus(More)