Denise M. McCarthy

Learn More
Generally, the surgical procedures employed in the treatment of patellofemoral joint (PFJ) osteoarthritis (OA) aim, either explicitly or implicitly, to alter the biomechanics of the osteoarthritic joint (i.e., improve motion and load transmission characteristics). Because of the mechanical nature of some of these surgical objectives, they can be evaluated(More)
Knee is a complex and articulated joint of the body. Cartilage is a smooth hyaline spongy material between the tibia and femur bones of knee joint. Cartilage morphology change is an important biomarker for the progression of osteoarthritis (OA). Magnetic resonance imaging (MRI) is the modality widely used to image the knee joint because of its hazard free(More)
Local infiltration analgesia (LIA) is an analgesic technique that has gained popularity since it was first brought to widespread attention by Kerr and Kohan in 2008. The technique involves the infiltration of a large volume dilute solution of a long-acting local anesthetic agent, often with adjuvants (e.g., epinephrine, ketorolac, an opioid), throughout the(More)
BACKGROUND AND PURPOSE MR imaging and MR spectroscopy are increasingly being used to determine response to pharmacologic therapy. Hepatic encephalopathy (HE) is characterized by abnormal cerebral metabolites, yet the response to lactulose and other anti-HE measures is still primarily determined by using arbitrary categorical clinical rating scales, rather(More)
  • 1