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StreptomeDB 2.0—an extended resource of natural products produced by streptomycetes
- Dennis Klementz, Kersten Döring, +8 authors Stefan Günther
- Medicine, Computer Science
- Nucleic Acids Res.
- 28 November 2015
Over the last decades, the genus Streptomyces has stirred huge interest in the scientific community as a source of bioactive compounds. The majority of all known antibiotics is isolated from these… Expand
Peptidoglycan Recycling in Gram-Positive Bacteria Is Crucial for Survival in Stationary Phase
ABSTRACT Peptidoglycan recycling is a metabolic process by which Gram-negative bacteria reutilize up to half of their cell wall within one generation during vegetative growth. Whether peptidoglycan… Expand
Wide Distribution of Foxicin Biosynthetic Gene Clusters in Streptomyces Strains – An Unusual Secondary Metabolite with Various Properties
Streptomyces diastatochromogenes Tü6028 is known to produce the polyketide antibiotic polyketomycin. The deletion of the pokOIV oxygenase gene led to a non-polyketomycin-producing mutant. Instead,… Expand