Learn More
Iron deficiency anemia is associated with lower plasma thyroid hormone concentrations in rodents and, in some studies, in humans. The objective of this project was to determine if plasma triiodothyronine (T3) and thyroxine (T4) kinetics were affected by iron deficiency. Studies were done at a near-thermoneutral temperature (30 degrees C), and a cool(More)
The impact of varying severities of iron-deficiency anemia on fasting blood glucose, plasma triiodothyronine, heart norepinephrine concentrations and resting oxygen consumption were evaluated. Male weanling Sprague-Dawley rats were assigned to one of six dietary groups (4, 6, 11, 16, 23 or 40 mg Fe/kg diet) for 6 wk. Hemoglobin, liver iron and transferrin(More)
Poor temperature regulation in both human and animal models has been associated with iron deficiency anemia. The review examines the evidence for causality in both animals and humans, as well as provides an overview of temperature regulation in homeotherms. A number of investigations conclude that anemia is a central component of the inability of(More)
Poor growth in iron deficiency is commonly observed in animal studies. Previous studies from our laboratory showed that iron-deficient rats are metabolically inefficient and have less body fat than controls and proposed that iron deficiency was related to increased metabolic rates and heat loss. To examine these points more completely, we examined growth(More)
Endovascular grafting represents a minimally invasive approach to prosthetic aortic grafting for abdominal aortic aneurysms (AAA). We reviewed our initial experience with a bifurcated endovascular graft that shares with conventional grafts the characteristics of discrete transaortic fixation and unitary unsupported woven polyester construction. Twenty-eight(More)
We examined changes in iron status in 25 female varsity collegiate swimmers over the course of a competitive season via weekly capillary blood sampling. We also studied the effectiveness of moderate iron supplementation (39 mg/day) in preventing expected changes in iron status via a double-blinded crossover design. On entry into the study, 17 of the(More)
To determine if the previously observed alterations in norepinephrine (NE) metabolism and resting metabolic rate in iron-deficient (ID) rats result from hypothyroidism, exogenous thyroxine (T4) and 3,5,3'-triiodothyronine (T3) were administered to ID rats in doses sufficient to normalize the plasma concentrations of these hormones, whereas other ID and(More)
  • 1