Denis Malvy

Khaled Ezzedine15
Pascal Millet7
Thierry Pistone7
Daouda Sissoko6
15Khaled Ezzedine
7Pascal Millet
7Thierry Pistone
6Daouda Sissoko
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Although the acute manifestations of Chikungunya virus (CHIKV) illness are well-documented, few data exist about the long-term rheumatic outcomes of CHIKV-infected patients. We undertook between June and September 2006 a retrospective cohort study aimed at assessing the course of late rheumatic manifestations and investigating potential risk factors(More)
  • Daouda Sissoko, Amrat Moendandze, Denis Malvy, Claude Giry, Khaled Ezzedine, Jean Louis Solet +1 other
  • 2008
BACKGROUND Since 2006, Chikungunya virus (CHIKV) has re-emerged as an important pathogen of global concern. However, individual and household factors associated with the acquisition and the magnitude of clinically silent CHIKV infections remain poorly understood. In this present study, we aimed to investigate the seroprevalence, estimate the proportion of(More)
  • Annie J. Sasco, Antoine Jaquet, Emilie Boidin, Didier K. Ekouevi, Fabian Thouillot, Thomas LeMabec +5 others
  • 2010
BACKGROUND With the lengthening of life expectancy among HIV-positive subjects related to the use of highly active antiretroviral treatments, an increased risk of cancer has been described in industrialized countries. The question is to determine what occurs now and will happen in the future in the low income countries and particularly in sub-Saharan Africa(More)
BACKGROUND Persistent symptoms, mainly joint and muscular pain and depression, have been reported several months after Chikungunya virus (CHIKV) infection. Their frequency and their impact on quality of life have not been compared with those of an unexposed population. In the present study, we aimed to describe the frequency of prolonged clinical(More)
BACKGROUND Active trachoma is not uniformly distributed in endemic areas, and local environmental factors influencing its prevalence are not yet adequately understood. Determining whether clustering is a consistent phenomenon may help predict likely modes of transmission and help to determine the appropriate level at which to target control interventions.(More)
BACKGROUND One year after the adoption of artesunate-amodiaquine (AS/AQ) as first-line therapy for the treatment of uncomplicated malaria, this study was designed to assess the treatment practices regarding anti-malarial drugs at health facilities in four rural areas in southern Cameroon. METHODS Between April and August 2005, information was collected by(More)
BACKGROUND This study was conducted to assess the impact of chikungunya on health costs during the epidemic that occurred on La Réunion in 2005-2006. METHODOLOGY/PRINCIPAL FINDINGS From data collected from health agencies, the additional costs incurred by chikungunya in terms of consultations, drug consumption and absence from work were determined by a(More)
  • Innocent Safeukui, Pascal Millet, Sébastien Boucher, Laurence Melinard, Frédéric Fregeville, Marie-Catherine Receveur +5 others
  • 2008
BACKGROUND A simple real-time PCR assay using one set of primer and probe for rapid, sensitive and quantitative detection of Plasmodium species, with simultaneous differentiation of Plasmodium falciparum from the three other Plasmodium species (Plasmodium vivax, Plasmodium ovale and Plasmodium malariae) in febrile returning travellers and migrants was(More)
  • Patrick Gérardin, Adrian Fianu, Denis Malvy, Corinne Mussard, Karim Boussaïd, Olivier Rollot +4 others
  • 2011
BACKGROUND Persistent disabilities are key manifestations of Chikungunya virus (CHIKV) infection, especially incapacitating polyarthralgia and fatigue. So far, little is known about their impact on health status. The present study aimed at describing the burden of CHIKV prolonged or late-onset symptoms on the self-perceived health of La Réunion islanders.(More)
BACKGROUND Chikungunya fever is an emerging arboviral disease characterized by an algo-eruptive syndrome, inflammatory polyarthralgias, or tenosynovitis that can last for months to years. Up to now, the pathophysiology of the chronic stage is poorly understood. CASE PRESENTATION We report the first case of CHIKV infection with chronic associated(More)