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Estrogens promote cell proliferation in normal and transformed mammary epithelial cells by inducing expression of hormone-responsive genes involved in the cell cycle. The action of antiestrogens is therefore central in regard to their potent inhibitory effects on estrogen-induced cell growth. We used normal human epithelial breast cells from primary(More)
The diagnostic worth and therapeutic value of laparoscopic surgery are known for ovarian cysts and ectopic pregnancies. Diagnosis of appendicitis is difficult, and laparoscopy is useful in these cases. The present study was done to assess the feasibility, efficacy, and advantages of a new laparoscopic appendectomy technique. Between August 1,1989, and July(More)
PURPOSE To prospectively evaluate the midterm results of uterine artery embolization for symptomatic adenomyosis. MATERIALS AND METHODS The study protocol was approved by the institutional review board, and all participants gave written informed consent. Eighteen women (mean age, 44.3 years) with symptomatic adenomyosis were treated with bilateral(More)
BACKGROUND The objective of this study was to assess efficacy and determine the optimal indication of selective arterial embolisation (SAE) in patients with life-threatening post-partum haemorrhage (PPH). METHODOLOGY/PRINCIPAL FINDINGS One hundred and two patients with PPH underwent SAE and were included from January 1998 to January 2002 in our university(More)
OBJECTIVE To investigate the effects of tibolone and its main metabolites on breast homeostasis. DESIGN In vitro studies in primary cultures of normal breast cells and in breast cancer cell lines. SETTING Hospital-based academic research center. PATIENT(S) Human breast cells were obtained from women undergoing surgery for hypermastia. Breast cancer(More)
BACKGROUND A transobturator tape is a nonwoven, thermally bonded polypropylene tape recently approved in Europe for minimally invasive treatment of stress urinary incontinence. CASE Three cases of obturator abscess after transobturator tape procedures are reported. Patients presented with groin pain and vaginal discharge, and physical examination showed(More)
A case of hyperreactio luteinalis in an otherwise normal pregnancy is reported. Ascites was present, but no peritoneal implants or adenopathy were seen. Findings that would have suggested the correct diagnosis are the symmetrical and bilateral pattern of the mass, as well as the rather uniform size of the loculi, which were 1 to 3 cm in diameter.
OBJECTIVE The objective of our report is to present three cases of vesicouterine fistulas secondary to a cesarean delivery, a uterine rupture during labor, and radiation therapy. The delay between the onset of symptoms and the diagnosis varied between 3 and 7 years. Different techniques such as color Doppler sonography, excretory urography, cystography, CT,(More)
N-Nitrosodibutylamine (NDBA) and its omega-oxidized metabolites N-nitrosobutyl-4-hydroxybutylamine (4-OH-NDBA) and N-nitrosobutyl-3-carboxypropylamine (BCPN) are potent urinary bladder carcinogens. To study putative organ specific activation of BCPN, its alpha-oxidation by liver and urinary bladder microsomal fractions was investigated in comparison to NDBA(More)