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The stimulation of vascular endothelial growth factor receptor-2 (VEGFR-2) by tumor-derived VEGF represents a key event in the initiation of angiogenesis. In this work, we report that VEGFR-2 is localized in endothelial caveolae, associated with caveolin-1, and that this complex is rapidly dissociated upon stimulation with VEGF. The kinetics of caveolin-1(More)
A new criterion for classifying multispectral remote sensing images or textured images by using spectral and spatial information is proposed. The images are modeled with a hierarchical Markov Random Field (MRF) model that consists of the observed intensity process and the hidden class label process. The class labels are estimated according to the maximum a(More)
The vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptors play essential and complementary roles in angiogenesis and combined inhibition of these receptors has been shown to result in potent antitumor activity in vivo. In this study, we report that ellagic acid (EA), a natural polyphenol found in fruits and nuts,(More)
—The aim of this paper is to study the contribution of intervehicle communication (IVC) to reduce the number of secondary collisions caused by an accident. We assess the impact of broadcast protocols used to disseminate warning messages and the impact of IVC penetration ratio on the number of collisions. There are two main contributions in this paper.(More)
The details and functional significance of the intrinsic horizontal connections between neurons in the motor cortex (MCx) remain to be clarified. To further elucidate the nature of this intracortical connectivity pattern, experiments were done on the MCx of three cats. The anterograde tracer biocytin was ejected iontophoretically in layers II, III, and V.(More)