Deng Yaozu

We don’t have enough information about this author to calculate their statistics. If you think this is an error let us know.
Learn More
The ligand-binding domain of VLDL receptor contains eight imperfectly similar repeats. To discuss the contribution of each repeat to ligand binding, the RT-PCR technique was used to clone the VLDLR-cDNA from the heart muscle of Chinese people. Two recombinants were further constructed, which contained the full-length cDNA of VLDLR and the mutant lacking(More)
To observe the inhibitory effects of an antisense u-PAR vector on invasion of highly invasive PC-3M cell subclones, the effects of the antisense u-PAR on activity of MMP-9 in those highly invasive cell subclones were detected by a quantitative RT-PCR and zymography. The monolayer invasion assay and colony formation assay in soft agar were used. And(More)
To evaluate the specific inhibition of antisense u-PAR on the u-PAR expressions in highly invasive cell subclones and to determine its blocking function in the invasion by those cells, a cDNA fragment of u-PAR obtained by RT-PCR was inserted into a plasmid vector named pcDNA3 in antisense orientation. Then the antisense u-PAR recombinant was transfected(More)
Mouse peritoneal macrophages (MPM) were incubated with ApoE-poor VLDL or ApoE rich VLDL at same concentrations for 24 h. The ApoE mRNA content increased in both groups than that in control and the highest ApoE mRNA content was seen in MPM incubated with ApoE poor VLDL. The results suggest that VLDL could stimulate ApoE gene expression in MPM and the(More)
  • 1