Skip to search formSkip to main contentSkip to account menu

Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia

In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.
View on Elsevier (opens in a new tab)

Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy

A relatively high mortality of severe coronavirus disease 2019 (COVID‐19) is worrying, and the application of heparin in COVID‐19 has been recommended by some expert consensus because of the risk of…
View on Elsevier (opens in a new tab)

Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2

Patients with severe pneumonia induced by SARS-CoV2 had higher platelet count than those induced by non-SARS- CoV2, and only the former with markedly elevated D-dimer may benefit from anticoagulant treatment.
View on Springer (opens in a new tab)

miR-638 Regulates Differentiation and Proliferation in Leukemic Cells by Targeting Cyclin-dependent Kinase 2*

The data suggest that miR-638 regulates proliferation and myeloid differentiation by targeting CDK2 and may serve as a novel target for leukemia therapy or marker for AML diagnosis and prognosis.
View on Publisher (opens in a new tab)

c-MYC and reactive oxygen species play roles in tetrandrine-induced leukemia differentiation

The results suggest that ROS generation and c-MYC suppression play important roles in tetrandrine-induced autophagy and differentiation, and the results from in vivo experiments were consistent with those from in vitro studies.
View on Springer (opens in a new tab)

Platelet-delivered ADAMTS13 inhibits arterial thrombosis and prevents thrombotic thrombocytopenic purpura in murine models.

Characterization of transgenic mice expressing recombinant human ADAMTS13 in platelets and its efficacy in inhibiting arterial thrombosis and preventing hereditary and acquired antibody-mediated TTP in murine models provide a proof of concept that platelet-delivered ADAMts13 may be explored as a novel treatment of arterialThrombotic disorders, including hereditary and acquisition TTP.
View on PubMed (opens in a new tab)

Effect of serum monoclonal protein concentration on haemostasis in patients with multiple myeloma

Haemostasis screening tests and serum monoclonal protein (M protein) concentration were retrospectively analysed in 101 patients newly diagnosed with multiple myeloma from January 2012 to April 2014 and found prolonged thrombin time was found in most of patients and was positively related to light-chain concentration.
View on Wolters Kluwer (opens in a new tab)

Validation of the PLASMIC score, a clinical prediction tool for thrombotic thrombocytopenic purpura diagnosis, in Chinese patients.

View on PubMed (opens in a new tab)

ANP32A regulates histone H3 acetylation and promotes leukemogenesis

The data indicate that ANP32A is a novel regulator of histone H3 acetylation and promotes leukemogenesis.
View on Springer (opens in a new tab)

Clinical characteristics of moderate and severe cases with COVID-19 in Wuhan, China: a retrospective study

Age, comorbidities, platelet count, albumin, D-dimer, LDH, CRP and IL-6 level might be more meaningful marks for COVID-19 prognostic evaluation.
View on Springer (opens in a new tab)
...
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)