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Evolution of the Isoprene Biosynthetic Pathway in Kudzu1[w]
TLDR
Whether or not a plant emits isoprene depends on whether or not it has a terpene synthase capable of using dimethylallyl diphosphate, as part of the long-term study ofIsoprene synthesis. Expand
Inhibitory kinetics and mechanism of kaempferol on α-glucosidase.
TLDR
It was proposed that kaempferol may interact with some amino acid residues located within the active site of α-glucosidase, occupying the catalytic center of the enzyme to avoid the entrance of p-nitrophenyl-α-D- glucopyranoside and ultimately inhibiting the enzyme activity. Expand
A newly identified polysaccharide from Ganoderma atrum attenuates hyperglycemia and hyperlipidemia.
  • K. Zhu, S. Nie, +5 authors M. Xie
  • Chemistry, Medicine
  • International journal of biological…
  • 1 June 2013
TLDR
Results indicated that PSG-1 may have a potential for the treatment of hyperglycemia, hyperlipidemia, hyperinsulinemia and insulin resistance in type 2 diabetes. Expand
Inhibitory effect of morin on tyrosinase: insights from spectroscopic and molecular docking studies.
TLDR
Analysis of circular dichroism spectra revealed that the binding of morin to tyrosinase induced rearrangement and conformational changes of the enzyme, and molecular docking results suggested that morin competitively bound to the active site of tyosinase with the substrate levodopa. Expand
Inhibitory Mechanism of Apigenin on α-Glucosidase and Synergy Analysis of Flavonoids.
TLDR
Isobolographic analysis of the interaction between myricetin and apigenin or morin showed that both of them exhibited synergistic effects at low concentrations and tended to exhibit additive or antagonistic interaction at high concentrations. Expand
Novel insights into the inhibitory mechanism of kaempferol on xanthine oxidase.
TLDR
The main inhibition mechanism of ka Kempferol on XO activity may be due to the insertion of kaempferol into the active site of XO occupying the catalytic center of the enzyme to avoid the entrance of the substrate and inducing conformational changes ofXO. Expand
Purification, physicochemical characterisation and anticancer activity of a polysaccharide from Cyclocarya paliurus leaves.
TLDR
A Cyclocarya paliurus (Batal.) Iljinskaja polysaccharide was isolated and purified by hot water extraction, ethanol precipitation, deproteinisation and anion-exchange chromatography and showed a strong inhibition effect on the growth of human gastric cancer HeLa cells. Expand
A Polysaccharide from Ganoderma atrum Improves Liver Function in Type 2 Diabetic Rats via Antioxidant Action and Short-Chain Fatty Acids Excretion.
TLDR
The results suggest that the improvement of PSG-1 on liver function in type 2 diabetic rats may be due to its antioxidant effects, SCFA excretion in the colon from PSg-1, and regulation of hepatic glucose uptake by inducing GLUT4 translocation through PI3K/Akt signaling pathways. Expand
Inhibitory mechanism of epicatechin gallate on α-amylase and α-glucosidase and its combinational effect with acarbose or epigallocatechin gallate
Abstract Suppression of α-amylase and α-glucosidase is favorable for improvement of postprandial hyperglycemia. Here, the inhibitory mechanisms of epicatechin gallate (ECG) on α-amylase andExpand
Chemoprotective effects of Ganoderma atrum polysaccharide in cyclophosphamide-induced mice.
  • Qiang Yu, S. Nie, +6 authors M. Xie
  • Chemistry, Medicine
  • International journal of biological…
  • 1 March 2014
TLDR
Findings indicate that PSG-1 plays an important role in the protection against myelosuppression and immunosuppressive and oxidative stress in Cy-treated mice and could be a potential immunomodulatory agent. Expand
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