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Clustering data by identifying a subset of representative examples is important for processing sensory signals and detecting patterns in data. Such "exemplars" can be found by randomly choosing an initial subset of data points and then iteratively refining it, but this works well only if that initial choice is close to a good solution. We devised a method(More)
Unsupervised categorization of images or image parts is often needed for image and video summarization or as a preprocessing step in supervised methods for classification, tracking and segmentation. While many metric-based techniques have been applied to this problem in the vision community , often, the most natural measures of similarity (e.g., number of(More)
Many kinds of data can be viewed as consisting of a set of vectors, each of which is a noisy combination of a small number of noisy prototype vectors. Physically, these prototype vectors may correspond to different hidden variables that play a role in determining the measured data. For example, a gene's expression is influenced by the presence of(More)
MOTIVATION We address the problem of multi-way clustering of microarray data using a generative model. Our algorithm, probabilistic sparse matrix factorization (PSMF), is a probabilistic extension of a previous hard-decision algorithm for this problem. PSMF allows for varying levels of sensor noise in the data, uncertainty in the hidden prototypes used to(More)
Effective visualization of biological data is often critical for subsequent analysis. The popular clustergram/dendrogram visualization rearranges rows and columns of a data matrix so as to highlight clusters of similar responses, but assumes each row or column belongs to only one cluster and cannot associate each row or column with multiple clusters. Such(More)
A key problem of interest to biologists and medical researchers is the selection of a subset of queries or treatments that provide maximum utility for a population of targets. For example, when studying how gene deletion mutants respond to each of thousands of drugs, it is desirable to identify a small subset of genes that nearly uniquely define a drug(More)
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