Learn More
The effect of lead on two calcium sensitive processes was determined. Micromolar concentrations of lead successfully replaced calcium in the activation of calmodulin-sensitive phosphodiesterase and in the promotion of potassium loss from erythrocytes. Both actions of lead were blocked by trifluoperazine--an inhibitor of calmodulin function. We propose that(More)
Phosphoinositide lipid metabolism and prostacyclin production are implicated in endothelium dependent vascular relaxation in large blood vessels. To determine if these biochemical pathways might be involved in the regulation of microvascular tone in the retina, we measured the formation of 6-keto-prostaglandin-F1 alpha, the stable end product of(More)
  • Delavari Ar, Yarahmadi Sh, Birjandi R, Mahdavi Ar, Norouzi Nejad, Dini M
  • 2006
ongenital Hypothyroidism (CH) is one of the most preventable causes of mental retardation and can be detected through neonatal screening; it is estimated 1200 CH patients are born in Iran, annually. The aim of this investigation was to provide a report on the outcome and estimate the cost-benefit ratio of the screening program implementation for CH in Iran(More)
  • 1