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Hierarchical modeling is wonderful and here to stay, but hyperparameter priors are often chosen in a casual fashion. Unfortunately, as the number of hyperparameters grows, the effects of casual choices can multiply, leading to considerably inferior performance. As an extreme, but not uncommon, example use of the wrong hyperparameter priors can even lead to(More)
In this article, we present an error estimate of the derivative approximation by the local multiquadricbased differential quadrature (LMQDQ) method. Radial basis function is different from the polynomial approximation, in which Taylor series expansion is not applicable. So, the present analysis is performed through the numerical solution of Poisson(More)
Fingolimod treatment initiation is associated with a transient slowing of heart rate and atrioventricular conduction. This report presents first-dose fingolimod effects (0.5mg or 1.25mg) on cardiac parameters using phase 3 FREEDOMS, FREEDOMS II and TRANSFORMS pooled study data (n=3635 patients). Vital signs were recorded hourly for ≥6h; 12-lead(More)
PURPOSE To report outcomes of ophthalmic evaluations in clinical studies of patients receiving fingolimod (Gilenya; Novartis Pharma AG, Basel, Switzerland) for multiple sclerosis (MS). DESIGN Analysis done on pooled safety data (N = 2615, all studies group) from 3 double-masked, randomized, parallel-group clinical trials (phase 2 core and extension >5(More)
IT enterprises generally believe that there is still a certain knowledge and skill gap between the demand of enterprises and IT professionals trained by the colleges and universities in China. IT students face enormous pressure in employment after graduation. As IT enterprises are the end-user of IT students, tertiary institutes should be market-oriented(More)
Hierarchical modeling is wonderful and here to stay, but hyperparameter priors are often chosen in a casual fashion. Unfortunately, as the number of hyperparameters grows, the effects of casual choices can multiply, leading to considerably inferior performance. As an extreme, but not uncommon, example use of the wrong hyperparameter priors can even lead to(More)
  • Dejun Tang
  • Eighth ACIS International Conference on Software…
  • 2007
In this paper, an observer applying for switched linear system with delays in state variables is proposed for the control of the system. The reduction of the conservatism is resolved by using of the switched Lyapunov function approach. Some results are also extended to the uncertain system. Several linear matrix inequalities (LMIs) are established to(More)
Active shape model (ASM) is a statistically parametrical model. It is widely used for facial feature extraction in face images. An ASM method is proposed. First, intensity values used in original ASM cannot provide enough information for model searching, which is sensitive to lighting conditions and so on. So we use a measure which indicates the orientation(More)