Deirdre Leane

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The exact mechanisms regulating conformational changes in the platelet-specific integrin alphaIIbbeta3 are not fully understood. However, a role exists for thiol/disulfide exchange in integrin conformational changes leading to altered disulfide bonding patterns, via its endogenous thiol isomerase activity. Nitric oxide (NO) accelerates this intrinsic(More)
The synthesis and a detailed investigation into the electronic properties of mononuclear and dinuclear Ru(II) complexes of the ligand bis(2-hydroxyphenyl)-2,5-dihydropyrazine (H(2)BHD) is described. In these complexes the Ru(II) moieties are bound through O,N coordination to an anionic phenolate and the pyrazine bridge. Relatively few reports are available(More)
A detailed spectroscopic and electrochemical study of a series of novel phenolate bound complexes, of general formulas [M(L-L)(2)(box)](PF(6)), where M is Os and Ru, L-L is 2,2-bipyridine or 2,2-biquinoline, and box is 2-(2-hydroxyphenyl)benzoxazole, is presented. The objectives of this study were to probe the origin of the LUMOs and HOMOs in these(More)
Voltammetric, photo-physical and photo-electrochemical properties of the Dawson polyoxometalate anions alpha-[S(2)M(18)O(62)](4-) (M = Mo, W) are presented, both in the presence and absence of a series of [Ru(II)L(n)](+/2+) cations [L(n) = (bpy)(3), (bpy)(2)(Im)(2), (bpy)(2)(dpq), (bpy)(2)(box) and (biq)(2)(box)]. Electrochemical processes for both the(More)
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