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Umbilical cord mesenchymal stem cells were isolated by a double enzyme digestion method. The third passage of umbilical cord mesenchymal stem cells was induced with heparin and/or basic fibroblast growth factor. Results confirmed that cell morphology did not change after induction with basic fibroblast growth factor alone. However, neuronal morphology was(More)
Diabetic nephropathy is the leading cause of end-stage renal disease. The aim of this study was to investigate the renoprotective effects of autologous transplantation of adipose-derived mesenchymal stem cells (ADMSCs) and to delineate its underlying mechanisms of action in diabetic nephropathy. Diabetes was induced(More)
PURPOSE To evaluate continuous and simultaneous variations of thread height and width for an experimental screw-type implant. MATERIALS AND METHODS A finite element model of an implant with a V-shaped thread was created. The range of thread height was set at 0.20 to 0.60 mm, and the range of thread width was set at 0.10 to 0.40 mm. Forces of 100 N and 50(More)
OBJECTIVE To determine the optimal thread pitch for an experimental cylinder implant in Ansys Work-bench Design Xplorer environment. METHODS Finite element models of segment jaw bone with a V-shaped thread implant were created. The thread pitch (P) was set from 0.5 mm to 1.6 mm. The maximum Equivalent stresses (EQV stresses) in jaw bone and in implant(More)
To make a direct biomechanical comparison between the sandblasted and acid-etched surface (SLA) and the machined and acid-etched surface (MA), a well-established animal model for implant removal torque testing was employed, using a split-mouth experimental design. All implants had an identical cylindrical solid-screw shape with the standard ITI thread(More)
OBJECTIVES The objectives of the present study were (1) to compare the stability of delayed loaded (DL) and immediately loaded (IL) ITI SLA implants during the first 3 months of the healing period using resonance frequency analysis (RFA) and (2) to determine the factors that affect implant stability during the healing period. MATERIALS AND METHODS To(More)
OBJECTIVE Diabetes mellitus may impair bone healing after dental implant placement. The objective of this study was to evaluate the effects of the local delivery of basic fibroblast growth factor (bFGF) from poly(lactide-co-glycolide) (PLGA) microspheres on osseointegration around titanium implants in diabetic rats. STUDY DESIGN The bFGF-PLGA microspheres(More)
OBJECTIVES To establish and experimentally validate a novel resonance frequency analysis (RFA) method for measurement of dental implant stability by analyzing torsional resonance frequency (TRF). MATERIAL AND METHODS A numerical study and in vitro measurements were performed to evaluate the feasibility and reliability of the method of torsional RFA(More)