Deepti Suri

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Percutaneous renal biopsy (PRB) is an important diagnostic tool in pediatric nephrology units. But controversy exists whether the procedure can be done in the day care setting. This study was done to document complications of PRB done with automated gun under continuous ultrasonographic guidance and to find whether the procedure can be undertaken as a day(More)
Chronic granulomatous disease (CGD) results from an inherited defect in the phagocytic cells of the immune system. It is a genetically heterogenous disease caused by defects in one of the five major subunits of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. There is a paucity of data from India on CGD. We herein describe the(More)
To assess complement levels C1q, C2, C3 and C4 in children with pediatric-onset lupus during the quiescent stage of disease. Thirty-four consecutive children with pediatric-onset SLE (onset below 12 years), in the quiescent stage were enrolled for the study. Twenty-nine age and sex matched healthy children were also enrolled for the purpose of comparison.(More)
Leukocyte adhesion deficiency (LAD) is a primary immuno-deficiency caused by a defect in the adherence of neutrophils to the wall of blood vessels. This failure in adherence results in an inability of transmigration of neutrophils through the endo-thelium to the site of inflammation [1]. Patients with LAD are predisposed to severe and life-threatening(More)
To the editor, Children with X-linked agammaglobulinemia (XLA) have a profound defect in B-lymphocyte development due to a mutation in BTK gene located on X chromosome. This results in severe hypogammaglobulinemia and an absence of circulating B cells. These children also have small to absent tonsils, and no palpable lymph nodes despite recurrent infections(More)
Pyoderma gangrenosum (PG) is an uncommon noninfectious neutrophilic dermatosis characterized by recurrent, sterile, necrotic skin ulcers. It is commonly associated with underlying systemic disease like inflammatory bowel disease, rheumatoid arthritis and hematological malignancies. Pathogenesis of PG remains unclear though aberrant immune responses have(More)
Good's syndrome is an eponymous, acquired immunological disorder characterized by the association of immunodeficiency with thymoma. It was first described six decades ago in 1954. The pathogenesis of this enigmatic disorder is still not clear although mutations in the TACI and BAFF-R genes have recently been reported. A 53-year-old male presented at our(More)