Deepkumar Joshi

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Different derivatives of chalcone-possessing benzimidazole as a prime motif were synthesized by the authors by acid catalyzed aldol condensation reaction. The synthesis of the desired compounds was initiated by undertaking two parallel reactions: (i) synthesis of 2-mercaptobenzimidazole and (ii) synthesis of N-(4-acetylphenyl)-2-chloroacetamide from(More)
Benzimidazole analogs bearing electron-withdrawing as well as electron-donating substituent were synthesized to achieve bioactive molecules with significant antimicrobial property. The desired compounds were prepared by multi-step synthesis process. The formation of intermediates and their corresponding derivatives (III 1–13 ) was confirmed by spectral(More)
The leaf and stem of cordia macleodii plant were investigated for evaluating antibacterial and antifungal properties. Different extracts of leaf and stem viz. double distilled water, methanol, ethyl acetate ane n-hexane were collected and content was optimized for the maximum amount of extraction with varying time of 6 and 12 h. The extracts were tested for(More)
A series of chalcones-bearing 1,3,4-oxadiazole derivatives was synthesized as novel bio-active antimicrobial agents against multidrug-resistant bacteria and fungi. The lead compounds (Z)-2-(5-(3-nitrophenyl)-1,3,4-oxadiazol-2-ylthio)-N-(4-(3-(aryl)acryloyl)phenyl)acetamides 5a–n were synthesized via acid-catalyzed aldol condensation (SOCl2) by reacting(More)
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