Deepali Singh

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Retroviruses rely on host RNA-binding proteins to modulate various steps in their replication. Previously several animal retroviruses were determined to mediate Dhx9/RNA helicase A (RHA) interaction with a 5' terminal post-transcriptional control element (PCE) for efficient translation. Herein PCE reporter assays determined HTLV-1 and HIV-1 RU5 confer(More)
Genome sequencing has not only extended our understanding of the blueprints of many plant species but has also revealed the secrets of coding and non-coding genes. We present here a brief introduction to and personal account of key RNA-based technologies, as well as their development and applications for functional genomics of plant coding and non-coding(More)
RNase P, which catalyzes tRNA 5'-maturation, typically comprises a catalytic RNase P RNA (RPR) and a varying number of RNase P proteins (RPPs): 1 in bacteria, at least 4 in archaea and 9 in eukarya. The four archaeal RPPs have eukaryotic homologs and function as heterodimers (POP5•RPP30 and RPP21•RPP29). By studying the archaeal Methanocaldococcus(More)
This paper provides an overview of service level agreements (SLAs) in IP networks. It looks at the typical components of an SLA and identifies three common approaches that are used to satisfy SLAs in IP networks. The implications of using the approaches in the context of a network service provider, a hosting service provider, and an enterprise are examined.(More)
Essential host cofactors in retrovirus replication bind cis-acting sequences in the 5'untranslated region (UTR). Although host RBPs are crucial to all aspects of virus biology, elucidating their roles in replication remains a challenge to the field. Here RNA affinity-coupled-proteomics generated a comprehensive, unbiased inventory of human and avian RNA(More)
Software Defect prediction is the pre-eminent area of software engineering which has witnessed huge importance over last decades. The identification of defects in the early stages of software development improve the quality of the software system and reduce the effort in maintaining the quality of software product. Many research studies have been conducted(More)
All decisions affecting the life cycle of human immunodeficiency virus (HIV-1) RNA are executed by ribonucleoprotein complexes (RNPs). HIV-1 RNA cycles through a progression of host RNPs composed of RNA-binding proteins regulating all stages of synthesis, processing, nuclear transport, translation, decay, and co-localization with assembling virions. RNA(More)
People have trusted in face-to-face interaction more than any other modes of interactions to develop relationships and as a result of which one of the most concerned problem that the electronic world is facing, is the lack of trust. For online trust development, study of customer behavior is must as customers, in present context, have become more fickle and(More)