Deena Hanke

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Nineteen of 71 (26%) cases of acute myelogenous leukemia (AML) were found to express CD7, a cell surface marker found early during T lineage differentiation. These myeloid leukemias often expressed other lymphoid markers and frequently had rearranged T-cell receptor beta and immunoglobulin heavy chain genes. We propose that in CD7+ AML, the malignant(More)
Intraperitoneal inoculation of neonate Sprague Dawley rats with cell-free extracts containing retrovirus-like particles from DMBA-induced rat mammary tumors resulted in a fivefold increase of benign mammary neoplasias in the survivor animals, in comparison to the spontaneous tumor incidence rate. In addition, four animals developed metastasizing abdominal(More)
OBJECTIVE To determine the prognostic value of analyzing lymph node (LN) DNA from patients with mycosis fungoides for the presence of a monoclonal T-cell population. DESIGN Inception cohort study. SETTING A tertiary care referral center in Seattle, Wash. PATIENTS Fifty-five uniformly staged patients with the diagnosis of mycosis fungoides and who had(More)
OBJECTIVE To extend previous observations regarding the prognostic value of analyzing lymph node DNA from patients with cutaneous T-cell lymphoma for the presence of a monoclonal T-cell population by Southern blot vs polymerase chain reaction (PCR) methods. DESIGN Inception cohort study from 1982 to 1998. Recruitment of new patients ended in 1994. (More)
Over human leg muscles, three motor responses (MR) can commonly be elicited, namely short-latency reflex (SLR), medium-latency reflex (MLR), and long-latency reflex (LLR). The MLR is less well understood than SLR and LLR. As the response to subsequent stimuli may be used to characterize central influences of an MR, we were interested, whether the MLR(More)
Pituitary necroses develop from the interruption of circulation in the pituitary stalk, especially due to shock, trauma, etc. We studied the incidence, extent, and outcome of necroses in postmortem series from 1991 to 1998 and compared these with the findings in our own study in the 1970s. Necroses were classified into four degrees based on the proportion(More)
Alterations of venous tone in superficial forearm veins, of peripheral venous pressure, skin- and muscle blood flow in the contralateral forearm, of heart rate and respiration were studied in healthy subjects during leg exercise in the supine position on a bicycle ergometer. After beginning of exercise there occured regularly increases in venous tone which(More)
Hypophysennekrosen sind Folge von Zirkulationsstörungen im Hypophysenstiel, z. B. bei Schockgeschehen, Trauma u. a. Wir untersuchten die Inzidenz, die Ausdehnung und das Schicksal der Nekrosen im Obduktionsgut der Jahre 1991–1998 im Vergleich zu einer eigenen Studie aus den 70er-Jahren. Die Nekrosen wurden in 4 Schweregrade eingeteilt (Grad I: bis 5%, Grad(More)
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