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Effects of Codonopis bulleynana forest ex diels on Deferribacteres in constipation predominant intestine tumor: Differential analysis
  • Y. Li, Y. Luan, +4 authors Z. Xiong
  • Biology, Medicine
  • Saudi journal of biological sciences
  • 6 December 2018
As a complicated micro-ecosystem, gut microbes are closely related to metabolic disease, immune disease and tumor (such as constipation. Long-term constipation would cause intestinal mucosal injury,Expand
  • 9
Codonopis bulleynana Forest ex Diels inhibits autophagy and induces apoptosis of colon cancer cells by activating the NF-κB signaling pathway
  • Y. Luan, Y. Li, +4 authors Y. Cao
  • Chemistry, Medicine
  • International journal of molecular medicine
  • 21 December 2017
Despite its favorable clinical efficacy, oxaliplatin-based chemotherapy frequently results in treatment withdrawal and induces liver damage in colon cancer. Therefore, it is important to developExpand
  • 8
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The effect of Codonopis bulleynana Forest ex Diels on chronically constipated mice
To verify the laxative effect of Codonopsis bulleyana and its effect on intestinal microbiota, a long-term constipation model was established using 3.0 mg/kg loperamide hydrochloride, after which,Expand
  • 1
RNA sequencing reveals the differences between chemical and chronic constipation induction of intestinal tumor
Constipation is a common clinical symptom and it is a highly frequent complication in patients with chronic gastrointestinal disorder and intestinal tumor. The chemicals such as DMHExpand
  • 5
Structural changes of gut microbiota in mice with chronic constipation and intestinal tumor
Background: Constipation is a highly frequent complication in patients with chronic gastrointestinal disorder and intestinal cancer. The purpose of this study was to evaluate the changes of gutExpand
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Changes of intestinal microflora diversity in diarrhea model of KM mice and effects of Psidium guajava L. as the treatment agent for diarrhea.
OBJECTIVES This study aimed to explore the effects of Psidium guajava L. extracts on mice diarrhea model and changes in their intestinal microflora diversity. METHODS Mice diarrhea model wasExpand
  • 2
Metabonomics of mice intestine in Codonopsis foetens induced apoptosis of intestine cancer cells
  • Y. Luan, Y. Li, +4 authors Z. Xiong
  • Chemistry, Medicine
  • Saudi journal of biological sciences
  • 16 November 2018
Intestinal cancer is a disease with high morbidity and high mortality in China. Previous studies have shown that Codonopsis foetens can inhibit cellular autophagy and promote the apoptosis ofExpand
Codonopis bulleynana Forest ex Diels (cbFeD) effectively attenuates hepatic fibrosis in CCl4-induced fibrotic mice model.
  • X. Li, Y. Xing, +12 authors Y. Luan
  • Chemistry, Medicine
  • Biomedicine & pharmacotherapy = Biomedecine…
  • 13 November 2020
The root of Codonopis bulleynana Forest ex Diels (cbFeD), a tonic food widely used in Yunnan Province of China, was found to have a wide range of pharmacological effects. The present study wasExpand