Debra A. Johnson

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Regression equations developed by Crawford, Allan & Jack (1992) to estimate full-length WAIS-R IQs from seven short-forms were evaluated in healthy (N = 153) and neurological (N = 471) cross-validation samples. In the healthy sample the correlations between the short-forms and full-length IQs did not differ significantly from those obtained by Crawford et(More)
In a prospective follow-up the outcome of 60 chronic schizophrenic patients who discontinued neuroleptic therapy after remaining stable 12-48 months was compared with controls continuing medication. Not only did the drug-discontinued patients have more relapses (P less than 0.001), but the form of relapse was both more severe and acute, resulting in(More)
A double-blind controlled trial of 50% dose reduction in maintenance treatment in stable out-patients with low BPRS scores and good social function shows a significantly higher relapse rate in the low-dose group at 12 months (P less than 0.05). After an interval of 24-36 months from dose reduction, 56-76% had experienced a relapse and 76-79% had resumed(More)
The authors reports on several studies of his own, namely two discontinuation studies and a survey of all known schizophrenic patients in a defined catchment area for a period of two years. Of the 140 patients prescribed a long-acting neuroleptic (LAN), 83% were still receiving injections after 2 years. Some 70% were responders, but 50% were rated on the(More)
  • D A Johnson
  • 1985
In clinical practice the benzodiazepines are prescribed almost as frequently as the tricyclic antidepressants for the treatment of depression. The therapeutic effects of the benzodiazepines and tricyclic antidepressants in depression have been compared in only 29 double-blind studies. The antidepressants proved overwhelmingly superior with only one study(More)
A survey of dust exposure, respiratory symptoms, lung function, and response to skin prick tests was conducted in a modern British bakery. Of the 318 bakery employees, 279 (88%) took part. Jobs were ranked from 0 to 10 by perceived dustiness and this ranking correlated well with total dust concentration measured in 79 personal dust samples. Nine samples had(More)
The incidence of relapse was compared between two groups of chronic schizophrenic patients (mean duration periods 19 months and 29.5 months) discontinuing depot neuroleptic injections, and matched controls remaining on depot injections. The results show a higher relapse rate in patients discontinuing injections, significant at the 1% level, in both groups.(More)
This paper presents preliminary data on the effects of physical exercise and virtual reality upon mood and cognition in severely brain injured adults. The work draws upon two established fields of experimental psychology, enriched environments and physical exercise, in order to propose a new orientation for neurological rehabilitation. The results will be(More)
A prospective study of schizophrenic patients prescribed injectable depot neuroleptic drugs as maintenance therapy showed a clinically significant weight gain in 55% of patients. No significant difference was shown between flupenthixol decanoate and fluphenazine decanoate, nor was a clinically meaningful relationship shown with dose, or the use of(More)
A double-blind comparison of fluphenazine decanoate and flupenthixol decanoate in 40 consecutive admissions showed no difference in anti-psychotic effect or extrapyramidal side effects after 56 days. However, the trial identified a different effect of the drugs on mood. Flupenthixol decanoate had an elating effect that was most marked during the week(More)