Deborah Saunders

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Chronic feeding of methyl-donor (methionine, choline, folic acid, and vitamin B12) deficient diet induces hepatocellular carcinoma formation in rats. Previous studies have shown that promoter CpG islands in various cancer-related genes are aberrantly methylated in this model. Moreover, the global genome in methyl-donor-deficient diet fed rats contains a(More)
ii Acknowledgments First of all, I would like to thank my Director Carol Flango for giving me the opportunity to participate in this program. Thanks also to my advisor and fearless leader, Dan Straub who helped to focus my study and keep me on track. To Joan Cochet and her team of interns, thank you for finding ―just one more article‖ for me again and(More)
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