Deborah M Levy

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OBJECTIVE To describe probabilities and characteristics of disease flares in children with juvenile idiopathic arthritis (JIA) and to identify clinical features associated with an increased risk of flare. METHODS We studied children in the Research in Arthritis in Canadian Children emphasizing Outcomes (ReACCh-Out) prospective inception cohort. A flare(More)
Purpose To determine the influence of ethnicity and sociodemo-graphic factors on disease presentation, manifestations, disease activity, and disease outcomes, using baseline data from the pediatric arm of the 1000 Canadian Faces of Lupus Study, a multicenter, prospective study of the Canadian Lupus population. Methods Childhood-onset SLE (<18 th birthday)(More)
Spinal epidural lipomatosis is a rare complication of chronic corticosteroid treatment. We report a new pediatric case and an analysis of this and 19 pediatric cases identified in the international literature. The youngest of these combined 20 patients was 5 years old when lipomatosis was diagnosed. Lipomatosis manifested after a mean of 1.3 (+/- 1.5) years(More)
Purpose Herpes zoster is reported to be one of the most common viral infections affecting Systemic Lupus Erythema-tosus (SLE) patients. The aim of the present study is to provide a descriptive analysis of the clinical features seen in childhood-onset SLE (cSLE) patients affected by herpes zoster. Methods A retrospective chart review of cSLE patients at one(More)
BACKGROUND : Therapy with mycophenolate mofetil (MMF) has become a valuable therapeutic option in children with autoimmune disease. MMF prescription in children with autoimmune diseases differs from that in transplant recipients in terms of different dosing regimen, and concomitant administration of other immunosuppressive medications. Recently, another(More)
OBJECTIVE To develop and initially validate a global cognitive performance score (CPS) for the Pediatric Automated Neuropsychological Assessment Metrics (PedANAM) to serve as a screening tool of cognition in childhood lupus. METHODS Patients (n = 166) completed the 9 subtests of the PedANAM battery, each of which provides 3 principal performance(More)
OBJECTIVE Behcet's is an idiopathic multi-organ syndrome, which may have onset during childhood. Vascular involvement is uncommon, with rarely reported coronary aneurysm formation. We present a case report of a teenager girl who developed recalcitrant life-threatening Behcet's vasculitis, involving both small and large venous and arterial systems including(More)
OBJECTIVES To examine the prescribing habits of NSAIDs among pediatric medical and surgical practitioners, and to examine concerns and barriers to their use. METHODS A sample of 1289 pediatricians, pediatric rheumatologists, sports medicine physicians, pediatric surgeons and pediatric orthopedic surgeons in the United States and Canada were sent an email(More)
Purpose The unpredictable disease course of childhood-onset sys-temic lupus erythematosus (cSLE) and its neuropsychiatric and cognitive symptoms can negatively impact quality of life at a time of major social, psychological and cognitive development. Quality of life (QoL) is multidimensional construct that describes a person's self perception of physical ,(More)
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