Deborah Leishman

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Customization involves fit and alterability and is based on understanding the commonality and variability (clv) across industries, geographies, customers, and systems. This paper argues for an emphasis on clv through a customization life cycle, from engineering customizable assets, components, and solutions to supporting their effective deployment. Examples(More)
Mishra et al.(1) in their article "Interaction between domperidone and ketoconazole: toward prediction of consequent QTc prolongation using purely in vitro information" describe the use of physiologically based pharmacokinetic (PBPK) modeling and pharmacodynamic models of cardiac repolarization to predict clinical data from preclinical data. Eliminating the(More)
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