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  • Gopi Shankar, Viswanath Devanarayan, +13 authors Eugen Koren
  • Chemistry, Medicine
  • Journal of pharmaceutical and biomedical analysis
  • 2008 (First Published: 1 December 2008)
  • Most biological drug products elicit some level of anti-drug antibody (ADA) response. This antibody response can, in some cases, lead to potentially serious side effects and/or loss of efficacy. InContinue Reading
  • Eugen Koren, H. Williams Smith, +15 authors Anthony Mire-Sluis
  • Medicine
  • Journal of immunological methods
  • 2008 (First Published: 1 April 2008)
  • The appropriate evaluation of the immunogenicity of biopharmaceuticals is of major importance for their successful development and licensure. Antibodies elicited by these products in many cases causeContinue Reading
  • Samuel Edwin Fineberg, Tom Kawabata, Deborah Finco-Kent, Cameron S. Liu, Alan Krasner
  • Medicine
  • The Journal of clinical endocrinology and…
  • 2005 (First Published: 1 June 2005)
  • OBJECTIVE To compare antibody responses to inhaled human insulin vs. sc human insulin and to determine whether insulin antibody binding is associated with adverse clinical consequences. RESEARCHContinue Reading
  • Deanna L Baker, Deborah Finco-Kent, William Joseph Reagan, Maryrose J. Conklyn, Thomas T. Kawabata
  • Medicine
  • Veterinary clinical pathology
  • 2008 (First Published: 1 March 2008)
  • BACKGROUND Guidelines published by the Food and Drug Administration and Center for Human Medicinal Products describe the need to assess immunotoxic effects in nonclinical studies that evaluate drugContinue Reading