Deborah C. Wang

Learn More
Two related forms of the respiratory-chain complex, NADH: ubiquinone oxidoreductase (Complex I) are synthesized in the mitochondria of Neurospora crassa. Normally growing cells make a large, piericidin-A-sensitive form, which consists of some 23 different nuclear- and 6-7 mitochondrially encoded subunits. Cells grown in the presence of chloramphenicol make(More)
This paper presents an optimum scheme for interconnecting the chip core and the I/O pads in the final stage of physical design. The pad placement routine, based on linear assignment, determines the dimension of the pad ring and selects the optimum position for each pad with the objective of minimizing the chip area and the total wire length. The router is(More)
In this paper we study the problem of distributing the set of crossings between two regions. A crossing is defined as the intersection of two nets. Three types of crossing-distribution problems are considered: (1) the quota problem, (2) the membership problem, and (3) the combination problem, which is a combination of the quota and membership problems. Our(More)
Five distinct low potential iron-sulfur clusters have been identified potentiometrically in the membrane particles from Thermus thermophilus HB-8. Three of these clusters (designated as [N-1H]T, [N-2H]T, and [N-3]T) exhibit the following midpoint redox potentials and g values (Em8.0 = -274 mV, gx,y,z = 1.93, 1.94, 2.02), (Em8.0 = -304 mV, gx,y,z = 1.89,(More)
Many biomedical data are in the form of time series. Analyses of these data include: (1) search for any biorhythm; (2) test of homogeneity of several time series; (3) assessment of stationarity; (4) test of normality of the time series histogram; (5) evaluation of dependence between data points. In this paper we present a subroutine package called TSAN. It(More)
1 In this paper, we propose a hybrid approach for estimating the switching activities of the internal nodes in logic circuits. The new approach combines the advantages of the simulation-based techniques and the probability-based techniques. We use the user-speci ed control sequence for simulation and treat the weakly correlated data inputs using the(More)
We propose a hybrid power model for estimating the power dissipation of a design at the RT-level. This new model combines the advantages of both RT-level and gate-level approaches. We investigate the relationship between steadystate transition power and overall power dissipation. We observe that, statistically, two input sequences causing similar amount of(More)
This paper examines leverage effect under a general setup that allows the log-price and volatility processes to be Itô semi-martingales and decomposes it into the continuous and the discontinuous part. The challenges in estimation consist in the various biases due to the latency of volatility and mutual interference between the Brownian and jump parts of(More)
A rapid and reliable analytical method is described for the simultaneous determination of RWJ-38705 (tramadol N-oxide) and several of its major metabolites in the plasma of Sprague-Dawley rats and Beagle dogs. Sample preparation using solid phase extraction was followed by reversed phase liquid chromatography (LC) coupled with tandem mass spectrometric(More)