Deborah A. Bowlby

Learn More
UNLABELLED Catamenial epileptics show particular vulnerability to seizures during menstruation and at the time of ovulation, when circulating estradiol (E(2))/progesterone (P(4)) ratios are high. The present study tested the hypothesis that alterations in neuronal excitability induced by E(2) and P(4) affect thresholds and the development of secondary(More)
Using a component processes model, the current study examined the cognitive processes of alcoholic and community control subjects engaged in the acquisition of new context-bound (e.g., episodic) information. Of particular interest was whether alcoholics were inferior to controls in the efficiency with which information was acquired and whether there was a(More)
The developmental effects of androgen play a central role in sexual differentiation of the mammalian central nervous system. The cellular mechanisms responsible for mediating these effects remain incompletely understood. A considerable amount of evidence has accumulated indicating that one of the earliest detectable events in the mechanism of sexual(More)
BACKGROUND/AIMS The contributions of the three principal ovarian steroid hormones (estradiol, progesterone and testosterone) to the regulation of estrogen receptor alpha (ERα) levels in the rat brain were examined during the estrous cycle. METHODS Receptor concentrations were measured using an in vitro autoradiographic technique designed to separately(More)
OBJECTIVE To develop an efficient surveillance approach for childhood diabetes by type across 2 large US health care systems, using phenotyping algorithms derived from electronic health record (EHR) data. MATERIALS AND METHODS Presumptive diabetes cases <20 years of age from 2 large independent health care systems were identified as those having ≥1 of the(More)
  • 1