Learn More
A volume-targeted contrast agent-enhanced breath-hold coronary magnetic resonance angiographic technique was optimized and evaluated in 16 volunteers. Substantial increases in coronary signal-to-noise ratio, contrast-to-noise ratio, lengths of depiction, and vessel sharpness were observed on enhanced images. The imaging approach with two 20-mL injections of(More)
The need for ECG gating presents many difficulties in cardiac magnetic resonance imaging (CMRI). Real-time imaging techniques eliminate the need for ECG gating in cine CMRI, but they cannot offer the spatial and temporal resolution provided by segmented acquisition techniques. Previous MR signal-based techniques have demonstrated an ability to provide(More)
Segmented cine MRI generally requires breath-holding, which can be problematic for many patients. Navigator echo techniques, particularly successful for free-breathing coronary MRA, are incompatible with the acquisition strategies and SSFP pulse sequences commonly used for cine MRI. The purpose of this work is to introduce a new self-gating technique(More)
PURPOSE To determine the relationship of pericardial fat, which secretes proinflammatory markers that have been implicated in coronary atherosclerosis, with atherosclerotic plaque in an asymptomatic population-based cohort. MATERIALS AND METHODS In this institutional review board-approved study, all participants supplied written informed consent. One(More)
ECG-based gating in cardiac MR imaging requires additional patient preparation time, is susceptible to RF and magnetic interference, and is ineffective in a significant percentage of patients. "Wireless" or "self-gating" techniques have been described using either interleaved central k-space lines or projection reconstruction to obtain MR signals(More)
BACKGROUND Despite the established role of late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) in characterizing chronic myocardial infarction (MI), a significant portion of chronic MI patients are contraindicative for the use of contrast agents. One promising alternative contrast free technique is diffusion weighted CMR (dwCMR), which(More)
PURPOSE To achieve whole-heart coronary magnetic resonance angiography (MRA) with (1.0 mm)(3) spatial resolution and 5 min of free-breathing scan time. METHODS We used an electrocardiograph-gated, T2-prepared and fat-saturated balanced steady state free precession sequence with 3DPR trajectory for free-breathing data acquisition with 100% gating(More)
PURPOSE To evaluate diagnostic performance of three nonenhanced methods: variable-refocusing-flip angle (FA) fast spin-echo (SE)-based magnetic resonance (MR) angiography (variable FA MR) and constant-refocusing-FA fast SE-based MR angiography (constant-FA MR) and flow-sensitive dephasing (FSD)-prepared steady-state free precession MR angiography (FSD MR)(More)
Epicardial fat, the local visceral fat depot enclosed by the visceral pericardial sac, surrounds the coronary arteries for most of their course, and may contribute to the development of coronary atherosclerosis through local production of inflammatory cytokines. Several studies which measured epicardial fat volume noninvasively have shown a relationship of(More)
PURPOSE To determine the feasibility of T2-weighted BOLD imaging for estimating regional myocardial oxygen extraction fraction (OEF) and approximating perfusion reserve (MPR) simultaneously in a canine model with moderate coronary artery stenosis. MATERIALS AND METHODS Eight mongrel dogs with moderate coronary artery stenosis underwent BOLD imaging at(More)