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We previously reported that laboratory reference strains of Chlamydia trachomatis differing in infection organotropism correlated with inactivating mutations in the pathogen's tryptophan synthase (trpBA) genes. Here, we have applied functional genomics to extend this work and find that the paradigm established for reference serovars also applies to clinical(More)
The purpose of this book is to provide the reader with vital communication concepts and tools to assist in preparing for and responding to a severe influenza pandemic in the United States. The focus of the book is on the possibility of a severe pandemic. Although the concepts do apply to less intense public health challenges, they may not need to be(More)
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