Debabrata Majumdar

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OBJECTIVES Chronic arsenic poisoning, due to ingestion of contaminated ground-water, is a major public health problem in West Bengal. It causes multiorgan damage. The present study attempts to objectively investigate the pulmonary involvement by examining the lung function. The nature of lung changes was also evaluated. MATERIAL AND METHODS One hundred(More)
OBJECTIVES Losartan, an angiotensin II receptor blocker, has portal hypotensive effects. This study evaluates the effect of losartan on portal pressure after 14 days and compares it with that of propranolol. METHODS A total of 39 individuals with cirrhosis were randomized into two groups of 19 and 20 patients each and were treated with losartan and(More)
Reports show that hepatopulmonary syndrome mostly occurs in the setting of advanced hepatic dysfunction, with the associated vasoactive substance imbalance believed to be responsible for its pathogenesis. However, hepatopulmonary syndrome has also been reported in cases of mild hepatic dysfunction or noncirrhotic portal hypertension, indicating that portal(More)
BACKGROUND Obstruction of the suprahepatic inferior vena cava (IVC) by a membrane or stricture is the commonest cause of Budd-Chiari syndrome in the eastern hemisphere. We present our experience with the outcome of balloon cavoplasty in such cases. METHODS We followed up 40 consecutive cases of Budd-Chiari syndrome over seven years. Doppler study of(More)
A field study was undertaken to investigate the effects of combined noise, vibration and heat stress on the physiological functions of the crew of armoured vehicles during prolonged combat exercise in a desert. The sound pressure level of noise was measured with a sound level meter and accelerations by vibration analyser. The thermal load on the crew was(More)
BACKGROUND/AIMS In cirrhosis, diastolic dysfunction of heart is well documented. Contribution of portal hypertension towards cardiac changes in cirrhosis is difficult to assess. We examined the patients of non-cirrhotic portal fibrosis who have portal hypertension without liver insufficiency to understand the contribution of portal hypertension in causing(More)
A cross-sectional study involving men in various age groups was carried out to evaluate some of the physiological and psychological correlates responsible for functional alteration with advancement of age. Each group consisted of 20 soldiers. Their resting physiological variables, lung function parameters, psychophysiological tests, and different mental(More)
In the present study a simple, accurate, precise, economical and specific UV-spectrophotometric method for estimation of besifloxacin in bulk and in different pharmaceutical formulation has been developed. The drug shows maximum λmax289 nm in distilled water, simulated tears and phosphate buffer saline. The linearity range of developed methods were in the(More)