Deanne Taylor

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Currently, the method most used for gene detection calls on Affy-metrix oligonucleotide arrays is provided as part of the MAS5.0 software. The MAS method uses Wilcoxon statistics for determining presence-absence (MAS-P/A) calls. It is known that MAS-P/A is limited by its need to use both perfect match (PM) and mismatch (MM) probe data in order to call a(More)
Aneuploidy represents the most prevalent form of genetic instability found in human embryos and is the leading genetic cause of miscarriage and developmental delay in newborns. Telomere DNA deficiency is associated with genomic instability in somatic cells and may play a role in development of aneuploidy commonly found in female germ cells and human(More)
An analysis of gene expression variability can provide an insightful window into how regulatory control is distributed across the transcriptome. In a single cell analysis, the inter-cellular variability of gene expression measures the consistency of transcript copy numbers observed between cells in the same population. Application of these ideas to the(More)
Residential, long-term care serves vulnerable older adults in a facility-based environment. A new care delivery model (CDM) designed to promote more equitable care for residents was implemented in a health region in Western Canada. Leaders and managers faced challenges in implementing this model alongside other concurrent changes. This paper explores the(More)
The 22q11.2 deletion syndrome (22q11DS; velocardiofacial/DiGeorge syndrome; VCFS/DGS; MIM #192430; 188400) is the most common microdeletion syndrome. The phenotypic presentation of 22q11DS is highly variable; approximately 60–75 % of 22q11DS patients have been reported to have a congenital heart defect (CHD), mostly of the conotruncal type, and/or aortic(More)
Gonadotropin-releasing hormone (GnRH) receptors are expressed in prostate cancer, specifically in the most aggressive stage of the tumor (castration-resistant prostate cancer, CRPC) for which the standard treatment, docetaxel-based chemotherapy, can only improve the median survival time by few months. We previously showed that GnRH agonists exert an(More)
  • Dan Brock, Robert C Berwick, Jeff W Bizzaro, Bioinformatics Org, Joseph Brennan, Dennis Fernandez +24 others
  • 2003
Welcome to the Proceedings of the Virtual Conference on Genomics and Bioinformatics. The objective of these and future proceedings reflects the goals of the conference itself: to share knowledge with the world. In this sense, the electronic versions will continue to be accessible at any time at the URL http://www.virtualgenomics.org. This issue contains(More)
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