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Effects of amylin-related peptides on food intake, meal patterns, and gastric emptying in rats.

• Roger D Reidelberger, Linda Kelsey, Dean G. Heimann
• American journal of physiology. Regulatory…
• 2002

We previously demonstrated that amylin inhibits food intake and gastric emptying in rats with half-maximal effective doses (ED(50)s) of 8 and 3 pmol x kg(-1) x min(-1) and maximal inhibitions of 78… (More)

Effects of peripheral CCK receptor blockade on gastric emptying in rats.

• Roger D Reidelberger, Linda S. Kelsey, Dean G. Heimann, Martin Hulce
• American journal of physiology. Regulatory…
• 2003

Type A CCK receptor (CCKAR) antagonists differing in blood-brain barrier permeability [devazepide penetrates; the dicyclohexylammonium salt of Nalpha-3-quinolinoyl-d-Glu-N,N-dipentylamide (A-70104)… (More)

Relaxin decreases the severity of established hepatic fibrosis in mice.

• Robert G. Bennett, Dean G. Heimann, Sudhir Pratap Singh, Ronda L Simpson, Dean J. Tuma
• Liver international : official journal of the…
• 2014

BACKGROUND & AIMS Hepatic fibrosis is characterized by excess collagen deposition, decreased extracellular matrix degradation and activation of the hepatic stellate cells. The hormone relaxin has… (More)

Effects of peripheral CCK receptor blockade on feeding responses to duodenal nutrient infusions in rats.

• Roger D Reidelberger, Dean G. Heimann, Linda S. Kelsey, Martin Hulce
• American journal of physiology. Regulatory…
• 2003

Type A cholecystokinin receptor (CCKAR) antagonists differing in blood-brain barrier permeability were used to test the hypothesis that duodenal delivery of protein, carbohydrate, and fat produces… (More)

Monocyte activation by an oral immunomodulator (bestatin) in lymphoma patients following autologous bone marrow transplantation

• Kazuhiko Ino, Philip Jay Bierman, +4 authors James E Talmadge
• Cancer Immunology, Immunotherapy
• 1996

 Bestatin (ubenimex), an inhibitor of aminopeptidase, is an oral immunomodulator that binds to CD13 (aminopeptidase N) on macrophages/monocytes. To examine its immunomodulatory effect after high-dose… (More)

Expression of green fluorescent protein in human foreskin fibroblasts for use in 2D and 3D culture models.

• Jie Chao, Tiffany Richelle Peña, +5 authors Mark A. Carlson
• Wound repair and regeneration : official…
• 2014

The availability of fibroblasts that express green fluorescent protein (GFP) would be of interest for the monitoring of cell growth, migration, contraction, and other processes within the… (More)

Degradation of relaxin family peptides by insulin-degrading enzyme.

• Robert G. Bennett, Dean G. Heimann, Frederick G. Hamel
• Annals of the New York Academy of Sciences
• 2009

Insulin-degrading enzyme (IDE) is a ubiquitously expressed metalloproteinase responsible for the intracellular degradation of insulin. IDE also interacts with other members of the insulin… (More)

Relaxin reduces fibrosis in models of progressive and established hepatic fibrosis.

• Robert G. Bennett, Dean G. Heimann, Dean J. Tuma
• Annals of the New York Academy of Sciences
• 2009

The effect of relaxin administration before (prevention) or after (treatment) the establishment of hepatic fibrosis in a mouse model was examined. In the prevention study, relaxin reduced collagen… (More)

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