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Therapeutic effects of DCDDP, a calcium channel blocker, on chronic pulmonary hypertension in rat.
- Zhi-chao Li, F. Zhang, Jing-chun Song, Q. Mei, De-hua Zhao
- Journal of applied physiology
- 1 March 2002
To explore the effect of dimethyl 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate (DCDDP) on pulmonary hypertension (PH) induced by monocrotaline (MCT), the parameters of… Expand
5-Hydroxytryptamine enhances L-type calcium current in norepinephrine-induced hypertrophic ventricular myocytes.
- Ming-gao Zhao, Q. Mei, +4 authors De-hua Zhao
- Chemistry, Medicine
- Acta pharmacologica Sinica
- 1 June 2002
AIM To study the effects of 5-hydroxytryptamine (5-HT) on L-type calcium current (ICa) in norepinephrine (NE)-induced hypertrophic ventricular myocytes. METHODS Left ventricular hypertrophy was… Expand
Effects of hexamatazidine on action potentials in guinea- pig papillary muscles
The effects of hexamatazidine (HMZ)on action potentials and slow response action potentials in guinea-pig papillary muscles were investigated using microelectrode technique. HMZ shorted action… Expand
Effects of IHC-72 on the ventricular muscle contraction induced by isoproterenol, calcium and histamine in guinea pigs
The effects of 3, 6(dimethylamino)-dibenzopyriodonium edetate (IHC 72) on the dose-response curves of isoproterenol, calcium and histamine in guinea-pig papillary muscles were studied. When… Expand
Identification on function of 5-HT anti-idiotypic monoclonal antibody
The cultured smooth muscle cells showed 5-HT receptor immunoreactivity. The length of smooth cells in normal medium was (187.8±35.4)mum. It became (175.6±43.3)mum, (160.2±46.2)mum, (116.9±25.8)mum,… Expand
blocker, on chronic pulmonary hypertension in rat Therapeutic effects of DCDDP, a calcium channel
Effects of 5-hydroxytryptamine on intracellular free Ca~(2+) of myocardium
AIM To observe the effects of 5-hydroxytryptam ine (5-HT) on intracellular free Ca 2+ of neonatal rat myocardium and to i nvestigate its mechanism. METHODS Neonatal rat myocardium was c ultured to… Expand