De-Ping Zhang

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Published data on the association between MDM2 309 T/G polymorphism and lung cancer risk are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. A total of eight studies including 6063 cases and 6678 controls were involved in this meta-analysis. Overall, significantly elevated lung cancer risk was associated(More)
OBJECTIVE To observe the effect and mechanism of curcumin on pulmonary fibrosis induced by bleomycin in rats. METHODS Fifty-four SD rats were randomly divided into 3 groups, 18 rats each group. The control group received a single intratracheal dose of 2 ml/kg of sterile physiological saline at day 0, and from 14 d, 0.5 ml/kg of sterile physiological(More)
Association and linkage studies of beta₂-adrenergic receptor (beta₂AR) polymorphisms in relation to the expression of asthmatic phenotypes and immune regulatory mechanisms have shown inconsistent results. This study was designed to analyze the relationship of particular combinations of single nucleotide polymorphisms (SNPs) or haplotypes of the beta₂AR gene(More)
BACKGROUND The role of the anti-apoptotic protein p27 in non-small cell lung cancer (NSCLC) remains controversial. To clarify its association with survival in NSCLC, we performed a systematic review of the literature with meta-analysis. METHODS Trials were selected for further analysis if they provided an independent assessment of p27 in NSCLC and(More)
The adverse effects of azithromycin on the treatment of patients with chronic lung diseases (CLD) were evaluated in the present study. MEDLINE and other databases were searched for relevant articles published until August 2013. Randomized controlled trials that enrolled patients with chronic lung diseases who received long-term azithromycin treatment were(More)
OBJECTIVE To describe the clinical and pathological features of primary NK/T cell lymphoma of the lung. METHODS Two cases of primary NK/T cell lymphoma of the lung were reported, and the clinical, radiological and pathological characteristics of the disease were discussed with literature review of 3 cases. RESULTS Most patients presented with fever,(More)
Although correlations between platelets and lung cancer has been recognized, effects on non-small cell lung cancer (NSCLC) metastasis remain to be determined in detail. In the present study, wound healing assays revealed a role of platelets in NSCLC cell migration . Thus the mean migration rate of lung adenocarcinoma A549 cells was significantly elevated(More)
OBJECTIVE To study the effects of curcumin on the expressions of collagen type I protein and transforming growth factor-beta1 mRNA in lung tissues of rats with pulmonary fibrosis. METHODS 96 male SD rats were randomly divided into four groups with 24 rats in each group: the normal control group, the model group, the prednisone treated group, and the(More)
OBJECTIVE To describe the imaging, clinical and pathological features of primary pulmonary involvement of NK/T-cell lymphoma. METHODS The imaging, clinical and pathological features of 2 patients with primary pulmonary involvement of NK/T-cell lymphoma were retrospectively analyzed. RESULTS The 2 cases (both young women) of NK/T-cell lymphoma were(More)