De-Chun Liu

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High expression of osmotically responsive genes 1 (HOS1) encodes an ubiquitin E3 ligase that promotes the degradation of transcription factor Inducer of CBF Expression 1 (ICE1). Inactivation of ICE1 reduces CBF-induced activation of many cold-responsive genes, and thus, HOS1 act as a negative regulator of cold-responsive genes. In this paper, a novel HOS1(More)
The altered ultrastructure and composition of cuticular wax from ‘glossy Newhall’ (MT) fruits lead to its glossy phenotype. A novel mutant derived from the wild-type (WT) ‘Newhall’ navel orange (Citrus sinensis [L.] Osbeck cv. Newhall), named ‘glossy Newhall’ (MT), which produced much more glossy fruits that were easily distinguishable from the WT fruits(More)
BACKGROUND This retrospective study and meta-analysis was designed to explore the relationship between E-cadherin (E-cad) expression and the molecular subtypes of invasive non-lobular breast cancer, especially in early-stage invasive ductal carcinoma (IDC). METHODS A total of 156 post-operative cases of early-stage IDCs were retrospectively collected for(More)
The aim of current study was to detect intron 22 inversion of factor VIII gene in severe hemophilia A (HA) patients and screen the carriers of the gene inversion. Fifty-five cases of severe HA were involved and factor VIII gene inversion was detected and identified by long distance-PCR (LD-PCR) and 0.6% agarose gel electrophoresis. The 11 kb and 12 kb bands(More)
AIM To construct a recombinant adeno-associated virus vector harboring fusion gene NT4-Apoptin-HA2-TAT, laying a foundation for gene therapy research of malignant tumors. METHODS The Apoptin and HA2-TAT gene were inserted in pUC19/NT4 vector after digested with restriction enzyme. The fusion gene of NT4-Apoptin-HA2-TAT was sub-cloned into the shuttle(More)
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