David Wrighton

Learn More
In recent years, real world objects have been used to reflect information previously shown on the computer screen. While most earlier efforts have required significant developer knowledge and skills to construct and program the displays, our work is investigating methods to enable programmers to use real world objects in much the same way that they would(More)
BACKGROUND AND PURPOSE The Slo3 (KCa 5.1) channel is a major component of mammalian KSper (sperm potassium conductance) channels and inhibition of these channels by quinine and barium alters sperm motility. The aim of this investigation was to determine the mechanism by which these drugs inhibit Slo3 channels. EXPERIMENTAL APPROACH Mouse (m) Slo3 (KCa(More)
In recent years, real world objects have been used to reflect information previously shown on the computer screen. While most earlier efforts have required significant developer knowledge and skills to construct and program the displays, our approach enables programmers to use real world objects in much the same way that they would typical user interface(More)
The patch clamp technique revolutionized the study of ion channels and is considered the gold standard of measuring ion channel activity, from the academic laboratory to industrial-scale drug screening. This technique enables the study of ion channels, from single molecules up to the whole-cell ion channel population, and in their native environment. Whilst(More)
  • 1