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The National Center for Biotechnology Information (NCBI) Reference Sequence (RefSeq) database is a collection of annotated genomic, transcript and protein sequence records derived from data in public sequence archives and from computation, curation and collaboration (http://www.ncbi.nlm.nih.gov/refseq/). We report here on growth of the mammalian and human(More)
Effective use of the human and mouse genomes requires reliable identification of genes and their products. Although multiple public resources provide annotation, different methods are used that can result in similar but not identical representation of genes, transcripts, and proteins. The collaborative consensus coding sequence (CCDS) project tracks(More)
Advances in semiconductor technology have let microprocessors integrate more than a 100 million transistors on a single chip. The Alpha 21364 microprocessor uses 152 million transistors to integrate an Alpha 21264 processor core, a 1.75-Mbyte second-level cache, cache coherence hardware, two memory controllers, and a multiprocessor router on a single die,(More)
The RefSeq project at the National Center for Biotechnology Information (NCBI) maintains and curates a publicly available database of annotated genomic, transcript, and protein sequence records (http://www.ncbi.nlm.nih.gov/refseq/). The RefSeq project leverages the data submitted to the International Nucleotide Sequence Database Collaboration (INSDC)(More)
The Consensus Coding Sequence (CCDS) project (http://www.ncbi.nlm.nih.gov/CCDS/) is a collaborative effort to maintain a dataset of protein-coding regions that are identically annotated on the human and mouse reference genome assemblies by the National Center for Biotechnology Information (NCBI) and Ensembl genome annotation pipelines. Identical annotations(More)
Interconnection networks usually consist of a fabric of interconnected routers, which receive packets arriving at their input ports and forward them to appropriate output ports. Unfortunately, network packets moving through these routers are often delayed due to conflicting demand for resources, such as output ports or buffer space. Hence, routers typically(More)
We have a new view of the time behavior of the inner solar corona via the extensive soft X-ray observations of Yohkoh. These show many forms of expansion of coronal material, ranging from highly collimated structures (jets) to large-scale evacuations ("dimmings") of the diffuse corona. We review these effects, emphasizing those probably related to CMEs, and(More)
Since its start, the Mammalian Gene Collection (MGC) has sought to provide at least one full-protein-coding sequence cDNA clone for every human and mouse gene with a RefSeq transcript, and at least 6200 rat genes. The MGC cloning effort initially relied on random expressed sequence tag screening of cDNA libraries. Here, we summarize our recent progress(More)
[1] We present the results of an investigation of the sequence of events from the Sun to the Earth that ultimately led to the 88 major geomagnetic storms (defined by minimum Dst 100 nT) that occurred during 1996–2005. The results are achieved through cooperative efforts that originated at the Living with a Star (LWS) Coordinated DataAnalysis Workshop (CDAW)(More)
[1] Seventy-nine major geomagnetic storms (minimum Dst 100 nT) observed in 1996 to 2004 were the focus of a ‘‘Living with a Star’’ Coordinated Data Analysis Workshop (CDAW) in March 2005. In nine cases, the storm driver appears to have been purely a corotating interaction region (CIR) without any contribution from coronal mass ejection-related material(More)