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  • Peter Batchelor, Gabriel T. Liberatore, +4 authors David W. Howells
  • Biology, Medicine
  • The Journal of Neuroscience
  • 1999 (First Publication: 1 March 1999)
  • Nigrostriatal dopaminergic neurons undergo sprouting around the margins of a striatal wound. The mechanism of this periwound sprouting has been unclear. In this study, we have examined the roleContinue Reading
  • David W. Howells, Michelle J Porritt, +5 authors Malcolm Robert Macleod
  • Medicine
  • Journal of cerebral blood flow and metabolism…
  • 2010 (First Publication: 1 August 2010)
  • No single animal model is able to encompass all of the variables known to affect human ischemic stroke. This review highlights the major strengths and weaknesses of the most commonly used animalContinue Reading
  • Emily S. Sena, H. Bart van der Worp, Philip M Bath, David W. Howells, Malcolm Robert Macleod
  • Medicine, Biology
  • PLoS biology
  • 2010 (First Publication: 1 March 2010)
  • Publication bias confounds attempts to use systematic reviews to assess the efficacy of various interventions tested in experiments modelling acute ischaemic stroke, leading to a 30% overstatement ofContinue Reading
  • Keith Hyland, Robert A H Surtees, Simon J R Heales, Ann Bowron, David W. Howells, Isabel Smith
  • Medicine
  • Pediatric Research
  • 1993 (First Publication: 1 July 1993)
  • ABSTRACT: Accurate diagnosis and management of inborn errors of monoamine neurotransmitter and tetrahydrobiopterin metabolism depend on reliable reference ranges of key metabolites. CerebrospinalContinue Reading
  • H. Bart van der Worp, Emily S. Sena, Geoffrey Alan Donnan, David W. Howells, Malcolm Robert Macleod
  • Medicine
  • Brain : a journal of neurology
  • 2007 (First Publication: 3 May 2007)
  • Induced hypothermia is proposed as a treatment for acute ischaemic stroke, but there have been too few clinical trials involving too few patients to draw any conclusions about the therapeutic benefitContinue Reading