David W. H. Walton

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UNLABELLED Weight loss remains the most common therapy advocated for reducing hepatic lipid in obesity and nonalcoholic fatty liver disease. Yet, reduction of body weight by lifestyle intervention is often modest, and thus, therapies which effectively modulate the burden of fatty liver but are not contingent upon weight loss are of the highest practical(More)
UNLABELLED Nonalcoholic fatty liver is frequently observed in obese individuals, yet the factors that predict its development and progression to liver disease are poorly understood. We proposed that proton magnetic resonance spectroscopy ((1)H-MRS) might allow noninvasive assessment of hepatic lipid composition. Lipid saturation (SI) and polyunsaturation(More)
Repetitive collapse of the upper airway during obstructive sleep apnea/hypopnea (OSA) exposes the brain of sufferers to frequent, transient, hypoxic episodes. The loss of cerebrovascular reactivity in sleep, and particularly in OSA, means that physiologic compensatory mechanisms may not ensure adequate brain oxygen levels. This (31)P magnetic resonance(More)
Ectoparasite collections from over 12,000 commensal rodents and shrews in Rangoon were examined. Rattus rattus, R. norvegicus, R. exulans and Bandicota bengalensis were found to host 12 species of trombiculid mites. Ascoschoengastia indica was the most abundant trombiculid found representing 84% of the total sample of 15,000 chiggers. This species (A.(More)
 Seeds of six endemic species and two circumpolar species were collected from several sites on Kerguelen and tested for germination between 5 and 25°C on thermogradient bars. Pringlea antiscorbutica and Colobanthus kerguelensis had a near 100% viability with an initial germination temperature of ca. 24°C. Colobanthus attained nearly 100% viability from 5 to(More)
Parametric and nonparametric analyses were used to investigate the relationships between the populations of viable microbes and 4 edaphic variables — soil moisture, rainfall, temperature, and pH. Microbial populations were sampled over a 2-year period in contrasting grass and moss stands on the subantarctic island of South Georgia. Moisture was found to be(More)
Leaves and litter of two phanerogams (Acaena magellanica (Lam.) Vahl and Poa flabellata (Lam.) Hook. f.) were collected in spring on the subantarctic island of South Georgia. Leaves immersed in water lost up to 80% of their total available soluble carbohydrates after 6–8 h. The loss of K+ and PO 4 3- followed a similar pattern to that shown by the(More)