David W. Feigal

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The potential medical applications of microarrays have generated much excitement, and some skepticism, within the biomedical community. Some researchers have suggested that within the decade microarrays will be routinely used in the selection, assessment, and quality control of the best drugs for pharmaceutical development, as well as for disease diagnosis(More)
The prefrontal cortex and basal ganglia are known to be crucial for learning arbitrary sensorimotor associations (e.g. knowing to stop at red traffic lights). However, little is known about the timing of learning-related activity in these brain systems. Conventional wisdom suggests that the prefrontal cortex should drive learning-related changes in the(More)
The efficacy and toxicity of pentamidine inhaled once a month to prevent Pneumocystis carinii pneumonia (PCP) was investigated in 102 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC). The cohort was compared with historical controls after a mean duration of prophylaxis of 6.38 months. 86% and 15% of the patients had(More)
The undersigned participated in the review process and preparation of this Report of the Independent Panel of Guidant Corporation. The Report is a consensus statement. No minority statements were submitted. 1 PREAMBLE Implantable cardiovascular devices have evolved as a major class of medical products used for the management of cardiovascular disorders.(More)
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