David T. Rollings

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The link between epilepsy and sleep is well established on many levels. The focus of the current review is on recent neuroimaging investigations into the alterations of consciousness that are observed during absence seizures and the descent into sleep. Functional neuroimaging provides simultaneous cortical and subcortical recording of activity throughout(More)
The transition from wakefulness into sleep is accompanied by modified activity in the brain's thalamocortical network. Sleep-related decreases in thalamocortical functional connectivity (FC) have previously been reported, but the extent to which these changes differ between thalamocortical pathways, and patterns of intra-thalamic FC during sleep remain(More)
OBJECTIVE The objective of this study was to investigate whether previously reported early blood oxygen level dependent (BOLD) changes in epilepsy could occur as a result of the modelling techniques rather than physiological changes. METHODS EEG-fMRI data were analysed from seven patients with focal epilepsy, six control subjects undergoing a visual(More)
Conventional functional connectivity (FC) analysis of fMRI data derives a single measurement from the entire scan, generally several minutes in duration, which neglects the brain's dynamic behaviour and potentially loses important temporal information. Short-interval dynamic FC is an attractive proposition if methodological issues can be resolved and the(More)
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