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- David Swigon, Bernard D. Coleman, Wilma K. Olson
- Proceedings of the National Academy of Sciencesâ€¦
- 2006

Repression of transcription of the Escherichia coli Lac operon by the Lac repressor (LacR) is accompanied by the simultaneous binding of LacR to two operators and the formation of a DNA loop. Aâ€¦ (More)

- Baris Hancioglu, David Swigon, Gilles Clermont
- Journal of theoretical biology
- 2007

We present a simplified dynamical model of immune response to uncomplicated influenza A virus (IAV) infection, which focuses on the control of the infection by the innate and adaptive immunity.â€¦ (More)

- Luke Czapla, David Swigon, Wilma K. Olson
- Journal of chemical theory and computation
- 2006

A new, computationally efficient Monte Carlo approach has been developed to estimate the ring-closure properties of short, realistically modeled DNA chains. The double helix is treated at the levelâ€¦ (More)

- Catherine L. Lawson, David Swigon, Katsuhiko S Murakami, Seth A Darst, Helen M. Berman, Richard H. Ebright
- Current opinion in structural biology
- 2004

Recently determined structures of the Escherichia coli catabolite activator protein (CAP) in complex with DNA, and in complex with the RNA polymerase alpha subunit C-terminal domain (alphaCTD) andâ€¦ (More)

- David Swigon, Brendan Coleman, IstvÃ¡n TÃ³biÃ¡s
- Biophysical journal
- 1998

Explicit solutions to the equations of equilibrium in the theory of the elastic rod model for DNA are employed to develop a procedure for finding the configuration that minimizes the elastic energyâ€¦ (More)

Explicit solutions of the equations of Kirchhoffâ€™s theory of elastic rods are employed to derive properties of the tertiary structure of a looped segment of DNA that is subject to geometricâ€¦ (More)

Methods are presented for obtaining exact analytical representations of supercoiled equilibrium configurations of impenetrable elastic rods of circular cross-section that have been pretwisted andâ€¦ (More)

- Irwin Tobias, David Swigon, Brendan Coleman
- Physical review. E, Statistical physics, plasmasâ€¦
- 2000

Results are presented in the theory of the elastic rod model for DNA, among which are criteria enabling one to determine whether a calculated equilibrium configuration of a DNA segment is stable inâ€¦ (More)

- Ericka Mochan, David Swigon, G. Bard Ermentrout, Sarah Lukens, Gilles Clermont
- Journal of theoretical biology
- 2014

The seriousness of pneumococcal pneumonia in mouse models has been shown to depend both on bacterial serotype and murine strain. We here present a simple ordinary differential equation model of theâ€¦ (More)

- Julia C. Arciero, Qi Mi, Maria F. Branca, David J. Hackam, David Swigon
- Biophysical journal
- 2011

Collective cell migration plays an important role during wound healing and embryo development. Although the exact mechanisms that coordinate such migration are still unknown, experimental studies ofâ€¦ (More)