David Stephen Rowlands

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Previous studies have suggested that common breast cancers are associated with EBV. We used a highly sensitive quantitative real-time PCR method to screen whole tumor sections of breast cancers for the presence of the EBV genome. EBV DNA was detected in 19 of 92 (21%) tumors, but viral load was very low in positive samples (mean = 1.1 copy EBV/1000 cells,(More)
Nutrition is an important aspect of recuperation for athletes during multi-day competition or hard training. Post-exercise carbohydrate is likely to improve recovery, but the effect of protein is equivocal. The objective of this study was to determine the effect of post-exercise dietary protein content imposed over a high-carbohydrate background on(More)
PURPOSE To determine whether combined ingestion of maltodextrin and fructose during 150 min of cycling exercise would lead to exogenous carbohydrate oxidation rates higher than 1.1 g.min. METHODS Eight trained cyclists VO2max: 64.1 +/- 3.1 mL.kg.min) performed three exercise trials in a random order. Each trial consisted of 150 min cycling at 55% maximum(More)
The dietary supplement beta-hydroxy-beta-methylbutyrate (HMB) is claimed to increase strength, lean body mass, and decrease fat mass when used in conjunction with resistance training. Although there is some support for these claims, the evidence is not conclusive, and it is even less so for resistance trained individuals. Therefore, we aimed to further(More)
The purpose of this study was to evaluate the effectiveness of two exercise modalities for improving glycosylated hemoglobin (HbA1c) and associated clinical outcomes in Polynesian adults diagnosed with type 2 diabetes and visceral obesity. Twenty-six adults were randomized to receive resistance training or aerobic training, 3×/week, for 16 weeks. Dependent(More)
INTRODUCTION Fructose coingested with glucose in carbohydrate (CHO) drinks increases exogenous-CHO oxidation, gut comfort, and physical performance. PURPOSE This study aimed to determine the effect of different fructose-maltodextrin-glucose ratios on CHO oxidation and fluid absorption while controlling for osmolality and caloricity. METHODS In a(More)
The respiratory exchange ratio (RER) is a valid method for determining fat and carbohydrate oxidation during exercise when the exchange of respiratory gas is in a state of steady flux between the tissue and fluid compartments and the alveoli. However, under incremental intensity or heavy exercise conditions, the movement of electrolytes, fluids, and CO2(More)
PURPOSE This study aimed to determine the effect of postexercise protein-leucine coingestion with CHO-lipid on subsequent high-intensity endurance performance and to investigate candidate mechanisms using stable isotope methods and metabolomics. METHODS In this double-blind, randomized, crossover study, 12 male cyclists ingested a leucine/protein/CHO/fat(More)
Oral curcumin decreases inflammatory cytokines and increases muscle regeneration in mice. To determine effects of curcumin on muscle damage, inflammation and delayed onset muscle soreness (DOMS) in humans. Seventeen men completed a double-blind randomized-controlled crossover trial to estimate the effects of oral curcumin supplementation (2.5 g twice daily)(More)
The effect of pre-exercise meal composition on metabolism and performance in cycling were investigated in a crossover study. Twelve competitive cyclists ingested high-fat, high-carbohydrate, or high-protein meals 90 min before a weekly exercise test. The test consisted of a 1-hour pre-load at 55% peak power, five 10-min incremental loads from 55 to 82% peak(More)