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UNLABELLED Ouabain stimulates activation of various signaling cascades such as protein kinase B (Akt) and Extracellular-signaling-regulated kinase 1/2 (ERK 1/2) in various cell lines. Retinoic acid (RA) is commonly used to induce neuroblastoma differentiation in cultures. Upon RA administration, human neuroblastoma cell line, SK-N-SH demonstrated neurite(More)
Tissue response to injury caused by the electrosurgical scalpel, the hemostatic Shaw scalpel, the CO2 laser, and a standard steel scalpel have been compared. Subcutaneous incisions in pigs were evaluated histologically at 1, 4, 7, 14, and 22 days postincision. The least damage was produced by the standard steel scalpel at all time periods. Epithelial(More)
Histological investigations were performed on 24 polyethylene terephthalate ligaments (eight Dacron, eleven Trevira and five Ligapro) which had served as substitute for the human anterior cruciate ligament. Because of rupture or loosening they had been explanted six to 48 months after operation. Only in one Trevira ligament a longitudinal direction of(More)
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