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BACKGROUND Seizure prediction would be clinically useful in patients with epilepsy and could improve safety, increase independence, and allow acute treatment. We did a multicentre clinical feasibility study to assess the safety and efficacy of a long-term implanted seizure advisory system designed to predict seizure likelihood and quantify seizures in(More)
BACKGROUND Use of automatic external defibrillators (AEDs) in children aged <8 years is not recommended. The purpose of this study was to develop an ECG database of shockable and nonshockable rhythms from a broad age range of pediatric patients and to test the accuracy of the Agilent Heartstream FR2 Patient Analysis System for sensitivity and specificity.(More)
Recently, deep neural networks (DNN) have been incorporated into i-vector-based speaker recognition systems, where they have significantly improved state-of-the-art performance. In these systems, a DNN is used to collect sufficient statistics for i-vector extraction. In this study, the DNN is a recently developed time delay deep neural network (TDNN) that(More)
BACKGROUND Delayed hematopoietic recovery is a major drawback of umbilical cord blood (UCB) transplantation. Transplantation of ex vivo-expanded UCB shortens time to hematopoietic recovery, but long-term, robust engraftment by the expanded unit has yet to be demonstrated. We tested the hypothesis that a UCB-derived cell product consisting of stem cells(More)
BACKGROUND Inhalation of airborne particulate matter (PM) derived from urban traffic is associated with pathology in the arteries, heart, and lung; effects on brain are also indicated but are less documented. OBJECTIVE We evaluated rodent brain responses to urban nanoscale (< 200 nm) PM (nPM). METHODS Ambient nPM collected near an urban freeway was(More)
A tool is described that provides for the automatic configuration of systems from a single description. The tool, newfig, uses two simple concepts to provide its functionality: boolean logic for making decisions and file construction for generating the files. Newfig relies heavily on external scripts for anything beyond the construction of files. This(More)
This report describes the development of an evidence-based guideline for external hemorrhage control in the prehospital setting. This project included a systematic review of the literature regarding the use of tourniquets and hemostatic agents for management of life-threatening extremity and junctional hemorrhage. Using the GRADE methodology to define the(More)
CASE Matthew, a healthy 18-month-old toddler, is seen for a health-supervision visit. The dietary history reveals that Matthew is breastfeeding and eats a variety of fruits, vegetables, cheese, yogurt, and grains. He is able to feed himself with a spoon, although he prefers to use his fingers. His height, weight, and head circumference have followed the(More)