David Shlensky

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Fig 2. Immunofluorescence analysis of CARM1 localization in human cell lines. (a, b) Localization of CARM1FL (E15) and total CARM1 (E16) in MDA-MB-231 cells. (c, d) Localization of CARM1FL (E15) and total CARM1 (E16) in BG-1 cells. (b) and (d) are quantification of immunofluorescence signals in cytoplasm and nucleus. DAPI: nuclear stain (blue). Phalloidin:(More)
PURPOSE Coactivator-associated arginine methyltransferase 1 (CARM1) is a coactivator for ERα and cancer-relevant transcription factors, and can methylate diverse cellular targets including histones. CARM1 is expressed in one of two alternative splice isoforms, full-length CARM1 (CARM1FL) and truncated CARM1 (CARM1ΔE15). CARM1FL and CARM1ΔE15 function(More)
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