David Schreiber

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The relationship between chromatin structure and gene expression is a subject of intense study. The universal transcriptional activator Gal4 removes promoter nucleosomes as it triggers transcription, but how it does so has remained obscure. The reverse process, repression of transcription, has often been correlated with the presence of nucleosomes. But it(More)
In this work we present an efficient GPU implementation of the Fast Directional Chamfer Matching (FDCM) algorithm [10]. We propose some extensions to the original FDCM algorithm. In particular, we extend the algorithm to handle templates with variable size, to account for perspective effects. To the best of our knowledge, our work is the first to present a(More)
PURPOSE To study the long-term outcomes and tolerance in our patients who received dose escalated radiotherapy in the early salvage post-prostatectomy setting. MATERIALS AND METHODS The medical records of 54 consecutive patients who underwent radical prostatectomy subsequently followed by salvage radiation therapy (SRT) to the prostate bed between(More)
PURPOSE To utilize the surveillance, epidemiology, and end results database to analyze whether there are racial or socioeconomic disparities associated with the selection of prostate brachytherapy. MATERIAL AND METHODS We selected patients who were diagnosed with localized prostate cancer between 2004-2006 and who underwent treatment with radiation. Data(More)
PURPOSE We analyzed outcomes of patients with prostate cancer undergoing either radical retropubic prostatectomy (RRP) +/- salvage radiation or definitive radiation therapy (RT) +/- androgen deprivation. MATERIALS AND METHODS From 2003-2010 there were 251 patients who underwent RRP and 469 patients who received RT (≥7,560 cGy) for prostate cancer.(More)