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The relationship between chromatin structure and gene expression is a subject of intense study. The universal transcriptional activator Gal4 removes promoter nucleosomes as it triggers transcription, but how it does so has remained obscure. The reverse process, repression of transcription, has often been correlated with the presence of nucleosomes. But it(More)
Interleukin 5 (IL-5) regulates the growth and function of eosinophils. The objective of this study was to investigate the intracellular signal transduction mechanism of IL-5 in eosinophils. Purified eosinophils were stimulated with IL-5, and the involvement of various kinases was investigated by immunoblotting, immune complex kinase assay, and in situ(More)
In this paper we present a background subtraction algorithm for a practical surveillance system, on a GPU. It utilizes a compressed non-parametric representation of the history of each pixel, using YCbCr color space, not requiring an offline training period. Although it can be parametrized to cope successfully with moving background, we rather focus on(More)
See Scherer (doi:10.1093/awv279) for a scientific commentary on this article.Charcot-Marie-Tooth type 1 neuropathies are inherited disorders of the peripheral nervous system caused by mutations in Schwann cell-related genes. Typically, no causative cure is presently available. Previous preclinical data of our group highlight the low grade, secondary(More)
In this work we present an efficient GPU implementation of the Fast Directional Chamfer Matching (FDCM) algorithm [10]. We propose some extensions to the original FDCM algorithm. In particular, we extend the algorithm to handle templates with variable size, to account for perspective effects. To the best of our knowledge, our work is the first to present a(More)