David Saunders

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AIM To describe the clinical spectrum of achiasmia, a congenital disorder of reduced relative decussation at the optic chiasm. METHODS A retrospective case note and patient review of nine children (four boys). Achiasmia was defined by the combination of a characteristic asymmetry of the monocular visual evoked potential (VEP) response to flash and(More)
PURPOSE To investigate whether longitudinal magnetic resonance proton spectroscopic imaging (MRSI) demonstrates regional metabolite abnormalities after traumatic brain injury (TBI) that predict long-term neurologic outcome. MATERIALS AND METHODS Two-dimensional-MRSI (point resolved spectroscopy sequence [PRESS]; TR/TE = 3000/144 msec; 10 mm) was acquired(More)
Forty-one patients presenting consecutively with acute angle closure glaucoma (AACG) were studied with a median follow-up period of eight months. Four patients presented with bilateral symptoms. Thirty-nine patients underwent Nd-YAG laser iridotomy (42 AACG eyes and 36 fellow eyes). Only 15 patients (36.6%) required simply iridotomy; the remainder required(More)
We report a case of orbital cellulitis after uneventful phacoemulsification and intraocular lens implantation under peribulbar injection. The eyelid skin was prepared with chlorhexidine gluconate before the peribulbar injection, and the eyelid and conjunctival cul-de-sac were prepared with povidone-iodine before phacoemulsification. Five days(More)
Prilocaine (Citanest) has been shown to be a satisfactory alternative to lignocaine, with certain important advantages, including superior diffusion. The latter may be especially important in peribulbar anesthesia, where the level of diffusion is a critical factor in providing a timely, high-quality block. In a prospective randomized study, we compared the(More)
OBJECTIVE To investigate the relationship between the ability of atlas-based autosegmentation to reduce outlining time in the male pelvis (body, bladder, rectum, femoral heads, prostate and seminal vesicles) and the interobserver agreement in the delineation of these structures. To examine any increase of the interobserver agreement with the use of an(More)
CONTEXT SOX3 is an early developmental transcription factor involved in pituitary development. In humans, over- and underdosage of SOX3 is associated with X-linked hypopituitarism with variable phenotypes ranging from isolated GH deficiency (GHD) to panhypopituitarism, with or without mental retardation and, in most cases, with reported pituitary imaging,(More)
A retrospective study was carried out to assess the success of the Fasanella-Servat procedure for the management of the aponeurotic defect type of adult ptosis. Eighteen procedures were carried out on 16 patients. The mean follow-up was 3 years. The success rate of the operation was 28% with a mean residual tarsal plate height of 5 mm with a very variable(More)